72326-72-8

Basic information

• Product Name: Benzene, 2-bromo-3,4,5-trimethoxy-1-methyl-
• CAS NO: 72326-72-8
• Molecular Formula: C10H13BrO3
• Molecular Weight: 261.115
• Mol File: 72326-72-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzene, 2-bromo-3,4,5-trimethoxy-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2-bromo-3,4,5-trimethoxy-1-methyl-(72326-72-8)
• EPA Substance Registry System: Benzene, 2-bromo-3,4,5-trimethoxy-1-methyl-(72326-72-8)

Safety Data

• Hazardous Substances Data: 72326-72-8(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 6443-69-2 3,4,5-trimethoxytoluene 
• 212573-50-7 (2,3,4-trimethoxy-6-methylphenyl)boronic acid 
• 73252-54-7 (2-bromo-3,4,5-trimethoxyphenyl)methanol 
• 81925-35-1 2-bromo-3,4,5-trimethoxybenzyl bromide 

Downstream Products

• 6443-69-2 3,4,5-trimethoxytoluene 
• 1204479-24-2 2,6-dibromo-3,4,5-trimethoxytoluene 
• 1432583-84-0 2-iodo-3,4,5-trimethoxy-1-methylbenzene 
• 1432583-87-3 dibutyl (2,3,4-trimethoxy-6-methylphenyl)boronate 
• 89048-14-6 1-(bromomethyl)-2,3,4,5-tetramethoxy-6-methylbenzene 
• 89048-58-8 2,3-dimethoxy-5-methyl-6-morpholinomethyl-1,4-benzoquinone 
• 127431-10-1 2-(4-benzoyl-piperazin-1-ylmethyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone 
• 35896-58-3 2,3,4,5-tetramethoxytoluene 
• 30685-17-7 2-bromo-5,6-dimethoxy-3-methylcyclohexane-2,5-diene-1,4-dione 
• 58186-28-0 2,3-dimethoxy-5-methyl-6-(10'-acetoxydecyl)-1,4-benzoquinone 
• 58186-27-9 Idebenone 
• 1286209-75-3 10-(2,3,4-trimethoxy-6-methylphenyl)decyl acetate 
• 1286209-77-5 C₂₂H₃₄O₅ 
• 1286209-74-2 10-(2,3,4-trimethoxy-6-methylphenyl)decan-1-ol 

Relevant articles and documents

Bromination of phenyl ether and other aromatics with bromoisobutyrate and dimethyl sulfoxide

Bromoisobutyrate has been used for the first time as a general brominating source for the direct bromination of a diverse of simple phenyl ethers. Aromatic ethers bearing various substituents could be compatible in this reaction system delivering brominated arenes in moderate to good yields. The reaction system can also be expanded to bromination of phenols and unactivated arene. This process can be regarded as an alternative for the well-established bromination systems for bromoarene synthesis.

A Concise Synthesis of Coenzyme Q0

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Efficient and Practical Oxidative Bromination and Iodination of Arenes and Heteroarenes with DMSO and Hydrogen Halide: A Mild Protocol for Late-Stage Functionalization

An efficient and practical system for inexpensive bromination and iodination of arenes as well as heteroarenes by using readily available dimethyl sulfoxide (DMSO) and HX (X = Br, I) reagents is reported. This mild oxidative system demonstrates a versatile protocol for the synthesis of aryl halides. HX (X = Br, I) are employed as halogenating reagents when combined with DMSO which participates in the present chemistry as a mild and inexpensive oxidant. This oxidative system is amenable to late-stage bromination of natural products. The kilogram-scale experiment (>95% yield) shows great potential for industrial application.