(5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol

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Chemical Name:(5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol
CAS No.:727348-59-6
Molecular Formula:C₂₉H₁₁F₁₅N₂O₂
Molecular Weight:704.395
Hs Code.:

(5-{[5-(hydroxy-pentafluorophenyl-methyl)-1<i>H</i>-pyrrol-3-yl]-pentafluorophenyl-methyl}-1<i>H</i>-pyrrol-2-yl)-pentafluorophenyl-methanol

Synonyms:(5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol

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Chemical Property of (5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol

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Technology Process of (5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol

There total 3 articles about (5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 522614-66-0
{5-[(5-pentafluorobenzoyl-1H-pyrrol-3-yl)-pentafluorophenyl-methyl]-1H-pyrrol-2-yl}-pentafluorophenyl-methanone

: 727348-59-6
(5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 20 ℃; for 8h;
DOI:10.1021/ol034227l

Reference yield:

pentafluorobenzoylchloride: 2251-50-5
pentafluorobenzoylchloride

: 727348-59-6
(5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 14 percent / AlCl₃ / CH₂Cl₂ / 38 h / Heating

2: NaBH₄ / tetrahydrofuran; methanol / 8 h / 20 °C

With sodium tetrahydroborate; aluminium trichloride; In tetrahydrofuran; methanol; dichloromethane; 1: Friedel-Crafts reaction;
DOI:10.1021/ol034227l

Reference yield:

: C₁₅H₉F₅N₂

: 727348-59-6
(5-{[5-(hydroxy-pentafluorophenyl-methyl)-1H-pyrrol-3-yl]-pentafluorophenyl-methyl}-1H-pyrrol-2-yl)-pentafluorophenyl-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 14 percent / AlCl₃ / CH₂Cl₂ / 38 h / Heating

2: NaBH₄ / tetrahydrofuran; methanol / 8 h / 20 °C

With sodium tetrahydroborate; aluminium trichloride; In tetrahydrofuran; methanol; dichloromethane; 1: Friedel-Crafts reaction;
DOI:10.1021/ol034227l