Chemical Property of Pentafluorobenzoyl chloride
Chemical Property:
- Appearance/Colour:clear colorless to light yellow liquid
- Vapor Pressure:2.91E-06mmHg at 25°C
- Refractive Index:n20/D 1.453(lit.)
- Boiling Point:158.504 °C at 760 mmHg
- Flash Point:49.662 °C
- PSA：17.07000
- Density:1.684 g/cm3
- LogP:2.76110
- Storage Temp.:2-8°C
- Sensitive.:Lachrymatory
- Water Solubility.:decomposes
- XLogP3:2.9
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:1
- Exact Mass:229.9557831
- Heavy Atom Count:14
- Complexity:222
- Purity/Quality:
-
99% *data from raw suppliers
Pentafluorobenzoyl Chloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
C
- Hazard Codes:C
- Statements:
14-34
- Safety Statements:
26-36/37/39-45
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1(=C(C(=C(C(=C1F)F)F)F)F)C(=O)Cl
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Description
Pentafluorobenzoyl chloride is the acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography. It has a role as a chromatographic reagent. It is an acyl chloride and a perfluorinated compound. It derives from a pentafluorobenzoic acid.2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivatize dimethylamine(DMA) in study to develop a rapid and accurate GC–MS method for determination of DMA in human urine. 2,3,4,5,6-Pentafluorobenzoyl chloride was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.
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Uses
Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines. A reagent used for deriving primary amines. 2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivative dimethylamine(DMA) in study to develop a rapid and accurate GC-MS method for determination of DMA in human urine. It was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry. Pentafluorobenzoyl chloride can be used for the derivatization of a variety of analytes including biological amines. There is an extensive use for the derivatization of lipids.
