1,2-Dihydrotanshinquinone

Base Information

Chemical Name:1,2-Dihydrotanshinquinone
CAS No.:77769-21-2
Molecular Formula:C₁₈H₁₄O₃
Molecular Weight:278.307
Hs Code.:
DSSTox Substance ID:DTXSID60998959
Nikkaji Number:J2.764.613A,J323.571H
Wikidata:Q82991780
Metabolomics Workbench ID:124972
ChEMBL ID:CHEMBL1813349
Mol file:77769-21-2.mol

Synonyms:1,2-dihydrotanshinquinone;1,2-DT-quinone;dan-shen root extract;Danshen extract;danshen root extract;methylenetanshinquinone;Salvia miltiorrhiza root;tanshinquinone, methylene-

Suppliers and Price of 1,2-Dihydrotanshinquinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
1,2-Dihydrotanshinquinone ≥98%
5mg
$ 568.00

Total 14 raw suppliers

Chemical Property of 1,2-Dihydrotanshinquinone

Chemical Property:

Vapor Pressure:5.81E-10mmHg at 25°C
Refractive Index:1.629
Boiling Point:495.6 °C at 760 mmHg
Flash Point:244.6 °C
PSA：47.28000
Density:1.286 g/cm³
LogP:3.98350
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:278.094294304
Heavy Atom Count:21
Complexity:521

Purity/Quality:

≥98% ^*data from raw suppliers

1,2-Dihydrotanshinquinone ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CCCC2=C1C=CC3=C2C(=O)C(=O)C4=C3OC=C4C

Technology Process of 1,2-Dihydrotanshinquinone

There total 7 articles about 1,2-Dihydrotanshinquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 96839-29-1
6-hydroxy-1,6-dimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione

: 77769-21-2
1,6-dimethyl-8,9-dihydrophenanthro[1,2-b]furan-10,11-dione

Guidance literature:: With toluene-4-sulfonic acid; In methanol; at 80 ℃; for 1h;
DOI:10.1039/c8ob00567b

Reference yield:

: 930-68-7
cyclohexenone

: 77769-21-2
1,6-dimethyl-8,9-dihydrophenanthro[1,2-b]furan-10,11-dione

Guidance literature:: Multi-step reaction with 5 steps

1: iodine; potassium carbonate; dmap / tetrahydrofuran; water / 1 h / 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; zinc dibromide / tetrahydrofuran / 7 h / -78 - 20 °C

3: diethyl ether / 0.5 h / 0 °C

4: methanol / 2 h / 45 °C / Inert atmosphere; Sonication

5: toluene-4-sulfonic acid / methanol / 1 h / 80 °C

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; potassium carbonate; toluene-4-sulfonic acid; zinc dibromide; In tetrahydrofuran; methanol; diethyl ether; water; 2: |Negishi Coupling / 3: |Grignard Reaction;
DOI:10.1039/c8ob00567b

Reference yield:

: 33948-36-6
2-iodocyclohex-2-en-1-one

: 77769-21-2
1,6-dimethyl-8,9-dihydrophenanthro[1,2-b]furan-10,11-dione

Guidance literature:: Multi-step reaction with 4 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; zinc dibromide / tetrahydrofuran / 7 h / -78 - 20 °C

2: diethyl ether / 0.5 h / 0 °C

3: methanol / 2 h / 45 °C / Inert atmosphere; Sonication

4: toluene-4-sulfonic acid / methanol / 1 h / 80 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; toluene-4-sulfonic acid; zinc dibromide; In tetrahydrofuran; methanol; diethyl ether; 1: |Negishi Coupling / 2: |Grignard Reaction;
DOI:10.1039/c8ob00567b