Dicloxacillin sodium

Base Information

• Chemical Name: Dicloxacillin sodium
• CAS No.: 13412-64-1
• Molecular Formula: C19H16Cl2N3NaO5S^.H2O
• Molecular Weight: 510.33
• Hs Code.: 29411099
• Mol file: 13412-64-1.mol

Synonyms:4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-,monosodium salt, monohydrate (8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, monohydrate, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, monohydrate, [2S-(2a,5a,6b)]-;3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl penicillin sodium saltmonohydrate;Dichlorstapenor sodium;Dicloxacillin sodium hydrate;Dicloxacillin sodium monohydrate;Dicloxacillin sodium salt hydrate;P 1011;Sodium dicloxacillin hydrate;Sodium dicloxacillin monohydrate;

Chemical Property of Dicloxacillin sodium

Chemical Property:

• Appearance/Colour: White to off-white crystalline powder
• Melting Point: 222-225 °C
• Boiling Point: 692.4 °C at 760 mmHg
• Flash Point: 372.5 °C
• PSA: 150.10000
• Density: g/cm³
• LogP: 2.13190
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble50mg/mL
• Water Solubility.: Soluble in water

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dicloxacillin sodium salt monohydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 36/37/38-42/43
• Safety Statements: 22-26-36/37-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Dicloxacillin sodium salt is used in the treatment of staphylococci resistant to penicillin G. Dicloxacillin binds to specific penicillin-binding proteins in the bacterial cell wall and therefore inhibits the last stage of bacterial cell wall synthesis. Cell lysis, mediated by bacterial cell wall autolytic enzymes, is the result. Dicloxacillin may interfere with autolysin inhibitors. A semi-synthetic antibiotic related to Penicillin. Antibacterial. Antibacterial;Bacterial transpeptidase inhibitor
• Therapeutic Function: Antibacterial

Technology Process of Dicloxacillin sodium

There total 1 articles about Dicloxacillin sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.7%

→ dicloxacillin sodium salt monohydrate (13412-64-1) + 6(3-(2,6-dichlorophenyl)-5-methylisoxazolyl-4-carboxyamido)-penicillanic acid sodium salt

Guidance literature:

Refernces