4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

Base Information

Chemical Name:4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile
CAS No.:943826-98-0
Molecular Formula:C₁₉H₁₄ClN₅O₂
Molecular Weight:379.805
Hs Code.:

Synonyms:4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

Suppliers and Price of 4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

There total 5 articles about 4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 943826-95-7
4-[4-(4-hydroxymethyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

: 943826-98-0
4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 20h;
DOI:10.1016/j.ejmech.2006.11.014

Reference yield:

: 943826-93-5
4-[2-(4-cyanophenylamino)pyrimidin-4-ylamino]-3-chloro-5-methoxybenzoic acid ethyl ester

: 943826-98-0
4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / LiAlH₄ / tetrahydrofuran / 20 h / 0 - 20 °C

2: 47 percent / MnO₂ / CH₂Cl₂ / 20 h / 20 °C

With manganese(IV) oxide; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.ejmech.2006.11.014

Reference yield:

: 943826-92-4
4-amino-3-chloro-5-methoxybenzoic acid ethyl ester

: 943826-98-0
4-[4-(4-formyl-2-chloro-6-methoxyphenylamino)pyrimidin-4-ylamino]benzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: hydrochloric acid / 16 h / Heating

2: 67 percent / LiAlH₄ / tetrahydrofuran / 20 h / 0 - 20 °C

3: 47 percent / MnO₂ / CH₂Cl₂ / 20 h / 20 °C

With hydrogenchloride; manganese(IV) oxide; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.ejmech.2006.11.014