(4-Chlorophenyl)diphenylsilane

Base Information

• Chemical Name: (4-Chlorophenyl)diphenylsilane
• CAS No.: 18557-60-3
• Molecular Formula: C₁₈H₁₅ClSi
• Molecular Weight: 294.856
• European Community (EC) Number: 660-614-5
• Nikkaji Number: J1.155.832A
• Mol file: 18557-60-3.mol

Synonyms:4-Chlorophenyldiphenylsilane;(4-CHLOROPHENYL)DIPHENYLSILANE;AKOS024338667

Chemical Property of (4-Chlorophenyl)diphenylsilane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 294.0631547
• Heavy Atom Count: 20
• Complexity: 255

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[SiH](C2=CC=CC=C2)C3=CC=C(C=C3)Cl

Technology Process of (4-Chlorophenyl)diphenylsilane

There total 5 articles about (4-Chlorophenyl)diphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromochlorobenzene (106-39-8) + diphenylsilyl chloride (1631-83-0) → (p-chlorophenyl)diphenylsilane (18557-60-3)

Guidance literature:

bromochlorobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2.5h;

diphenylsilyl chloride; In tetrahydrofuran; at -78 - 20 ℃; for 8h;

DOI:10.1002/anie.202010437

Reference yield:

chloro(4-chlorophenyl)diphenylsilane (18557-81-8) → (p-chlorophenyl)diphenylsilane (18557-60-3)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja01151a119

Reference yield:

(4-chlorphenyl)magnesium bromide (873-77-8) → (p-chlorophenyl)diphenylsilane (18557-60-3)

Guidance literature:

Multi-step reaction with 2 steps

2: LiAlH₄

With lithium aluminium tetrahydride;

DOI:10.1021/ja01151a119

upstream raw materials:

chloro(4-chlorophenyl)diphenylsilane

(4-chlorphenyl)magnesium bromide

diphenylsilyl dichloride

bromochlorobenzene

Downstream raw materials:

(bromomethyl)(p-chlorophenyl)diphenylsilane

(4-chlorophenyl)diphenylsilanol