(4-chlorophenyl)diphenylsilanol

Base Information

• Chemical Name: (4-chlorophenyl)diphenylsilanol
• CAS No.: 58292-98-1
• Molecular Formula: C₁₈H₁₅ClOSi
• Molecular Weight: 310.855
• Mol file: 58292-98-1.mol

Synonyms:(4-chlorophenyl)diphenylsilanol

Chemical Property of (4-chlorophenyl)diphenylsilanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-chlorophenyl)diphenylsilanol

There total 3 articles about (4-chlorophenyl)diphenylsilanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(p-chlorophenyl)diphenylsilane (18557-60-3) → (4-chlorophenyl)diphenylsilanol (58292-98-1)

Guidance literature:

With N-hydroxyphthalimide; water; tert-butylammonium hexafluorophosphate(V); In acetonitrile; at 20 ℃; for 8h; Electrolysis; Inert atmosphere;

DOI:10.1002/anie.202010437

Reference yield: 55.8%

→ (4-chlorophenyl)diphenylsilanol (58292-98-1)

Guidance literature:

With [RhCl₂(p-cymene)]2; water; In acetonitrile; at 20 ℃; for 12h; Inert atmosphere;

Reference yield:

bromochlorobenzene (106-39-8) + diphenylsilyl chloride (1631-83-0) → (4-chlorophenyl)diphenylsilanol (58292-98-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 2.5 h / -78 °C

1.2: 8 h / -78 - 20 °C

2.1: N-hydroxyphthalimide; tert-butylammonium hexafluorophosphate(V); water / acetonitrile / 8 h / 20 °C / Electrolysis; Inert atmosphere

With n-butyllithium; N-hydroxyphthalimide; water; tert-butylammonium hexafluorophosphate(V); In tetrahydrofuran; acetonitrile;

DOI:10.1002/anie.202010437

upstream raw materials:

bromochlorobenzene

diphenylsilyl chloride

(p-chlorophenyl)diphenylsilane