Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

Base Information

Chemical Name:Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide
CAS No.:112230-10-1
Molecular Formula:C₁₈H₂₁N₃O₃S
Molecular Weight:359.449
Hs Code.:

Synonyms:Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

Suppliers and Price of Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

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Technology Process of Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

There total 4 articles about Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 10147-36-1
n-propanesulfonyl chloride

: 105785-70-4
3-[(1-methyl-2-benzimidazolyl)methoxy]benzenamine

: 112230-10-1
Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

Guidance literature:: With triethylamine; In tetrahydrofuran; Ambient temperature;
DOI:10.1021/jm00126a006

Reference yield:

: 4760-35-4
2-chloromethyl-1-methyl-1H-benzimidazole

: 112230-10-1
Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: Cs₂CO₃ / acetone / Heating

2: H₂ / Raney nickel / ethanol

3: 34 percent / Et₃N / tetrahydrofuran / Ambient temperature

With hydrogen; caesium carbonate; triethylamine; nickel; In tetrahydrofuran; ethanol; acetone;
DOI:10.1021/jm00126a006

Reference yield:

: 554-84-7
meta-nitrophenol

: 112230-10-1
Propane-1-sulfonic acid [3-(1-methyl-1H-benzoimidazol-2-ylmethoxy)-phenyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: Cs₂CO₃ / acetone / Heating

2: H₂ / Raney nickel / ethanol

3: 34 percent / Et₃N / tetrahydrofuran / Ambient temperature

With hydrogen; caesium carbonate; triethylamine; nickel; In tetrahydrofuran; ethanol; acetone;
DOI:10.1021/jm00126a006