Technology Process of C14H25NO3
There total 6 articles about C14H25NO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl (1R,5R)-5-isopropyl-2-methylcyclohex-2-enylcarbamate;
With
potassium hexamethylsilazane;
In
tetrahydrofuran;
at 0 ℃;
for 1h;
Inert atmosphere;
chloromethyl methyl ether;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 4h;
Inert atmosphere;
DOI:10.1021/ol200312q
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium carbonate / N,N-dimethyl-formamide / 4 h / 150 °C / Inert atmosphere
2.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
2.2: 4 h / 0 - 20 °C / Inert atmosphere
With
potassium hexamethylsilazane; sodium carbonate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ol200312q
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: platinum(IV) oxide; hydrogen
2.1: lithium aluminium tetrahydride / diethyl ether / -50 - -10 °C / Inert atmosphere
3.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 1.33 h / 0 °C / Inert atmosphere
4.1: potassium carbonate / 5,5-dimethyl-1,3-cyclohexadiene / 6 h / Inert atmosphere; Reflux
5.1: sodium carbonate / N,N-dimethyl-formamide / 4 h / 150 °C / Inert atmosphere
6.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
6.2: 4 h / 0 - 20 °C / Inert atmosphere
With
platinum(IV) oxide; lithium aluminium tetrahydride; hydrogen; potassium hexamethylsilazane; sodium carbonate; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
4.1: Overmann rearrangement;
DOI:10.1021/ol200312q
