1274795-58-2

Upstream product

• 67-56-1 methanol 
• 1274795-53-7 2,2,2-trichloro-N-((1R,5R)-5-isopropyl-2-methylcyclohex-2-enyl)acetamide 
• 499-71-8 carvotanacetone 
• 536-30-1 (+)-cis-(1S,5S)-5-isopropyl-2-methyl-2-cyclohexen-1-ol 

Downstream Products

• 1274795-61-7 C₂₀H₂₉NO₅ 
• 1274795-60-6 C₁₈H₂₇NO₄ 
• 1274795-59-3 C₁₄H₂₅NO₃ 
• 1561030-12-3 (3aR,6R,7aR,E)-3-(4-hydroxybutylidene)-6-isopropyl-1,3a-dimethyl-3,3a,7,7a-tetrahydro-1H-indol-2(6H)-one 
• 1561029-86-4 (3aR,6R,7aR,E)-6-isopropyl-3-(4-(4-methoxybenzyloxy)butylidene)-1,3a-dimethyl-3,3a,7,7a-tetrahydro-1H-indol-2(6H)-one 
• 1561029-79-5 (1R,5R)-5-isopropyl-N,2-dimethylcyclohex-2-enamine 

Relevant academic research and scientific papers

Asymmetric synthesis of the tricyclic core of calyciphylline A-type alkaloids via intramolecular [3 + 2] cycloaddition

Asymmetric synthesis of the [5-6-7] tricyclic system common to the Calyciphylline A-type alkaloids is reported, featuring Overman rearrangement, Heck cyclization, intramolecular [3 + 2] cycloaddition, diastereoselective hydrogenation, and Claisen rearrangement as strategic events. The approach is capable of installing the crucial carbonyl functionality as well as multiple stereogenic centers within a congested polycyclic ring skeleton.

Rapid construction of [5-6-7] tricyclic ring skeleton of calyciphylline alkaloid daphnilongeranin B

A concise photochemical [2 + 2] cycloaddition-Grob fragmentation sequence sets the common tricyclic ring skeletons of the Calyciphylline A-type alkaloids, particularly those in daphnilongeranins, daphniyunnines, and daphniglaucins.