3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one

Base Information

• Chemical Name: 3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one
• CAS No.: 190323-49-0
• Molecular Formula: C₂₀H₂₀O₈
• Molecular Weight: 388.374
• Mol file: 190323-49-0.mol

Synonyms:3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one

Chemical Property of 3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one

There total 21 articles about 3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.2%

5,7-dihydroxy-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-2-(3, 4,5-trihydroxyphenyl)-4H-chromen-4-one + methyl iodide (74-88-4) → 3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one (190323-49-0)

Guidance literature:

5,7-dihydroxy-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-2-(3, 4,5-trihydroxyphenyl)-4H-chromen-4-one; methyl iodide; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In ethanol; water; Reflux;

DOI:10.1016/j.ejmech.2018.07.013

Reference yield: 76.0%

C20H18O13 + methyl iodide (74-88-4) → 3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one (190323-49-0)

Guidance literature:

C₂₀H₁₈O₁₃; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

Reference yield: 75.22%

myricitrin (17912-87-7) + methyl iodide (74-88-4) → 3-hydroxy-5,7-dimethoxy-2–(3,4,5-trimethoxyphenyl)-4H-chromen-4-one (190323-49-0)

Guidance literature:

myricitrin; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

With hydrogenchloride; In ethanol; water; for 2h; Reflux;

upstream raw materials:

isopentyl nitrite

diazomethane

dimethyl sulfate

3-hydroxy-5,7-dimethoxy-2-(3,4,5-trimethoxy-phenyl)-chroman-4-one