Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

Base Information

Chemical Name:Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane
CAS No.:163228-81-7
Molecular Formula:C₂₁H₃₆O₃Si
Molecular Weight:364.601
Hs Code.:

Synonyms:Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

Suppliers and Price of Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

There total 4 articles about Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 89238-99-3
O-(4-methoxybenzyl)-trichloroacetimidate

: 158586-21-1
(2R,3S,4R)-4-methyl-2-(triethylsilyloxy)-5-hexen-3-ol

: 163228-81-7
Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

Guidance literature:: With camphor-10-sulfonic acid; In hexane; at 25 ℃; for 72h;
DOI:10.1246/bcsj.68.967

Reference yield:

: 994-30-9
triethylsilyl chloride

: 163228-81-7
Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / imidazole / dimethylformamide / 2.5 h / 25 °C

2: DIBAL / CH₂Cl₂ / 3.5 h / -78 °C

3: 1.) t-BuOK, n-BuLi, 2.) B-(-)-methoxydiisopinocampheylborane, 3.) BF₃*OEt₂, 4.) aq. H₂O₂, aq. NaOH

4: 55 percent / CSA / hexane / 72 h / 25 °C

With 1H-imidazole; sodium hydroxide; n-butyllithium; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; potassium tert-butylate; dihydrogen peroxide; diisobutylaluminium hydride; (-)-B-methoxydiisopinocampheylborane; In hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.68.967

Reference yield:

: 158586-20-0
(2R)-2-(triethylsilyloxy)propionaldehyde

: 163228-81-7
Triethyl-[(1R,2S,3R)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-pent-4-enyloxy]-silane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) t-BuOK, n-BuLi, 2.) B-(-)-methoxydiisopinocampheylborane, 3.) BF₃*OEt₂, 4.) aq. H₂O₂, aq. NaOH

2: 55 percent / CSA / hexane / 72 h / 25 °C

With sodium hydroxide; n-butyllithium; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; potassium tert-butylate; dihydrogen peroxide; (-)-B-methoxydiisopinocampheylborane; In hexane;
DOI:10.1246/bcsj.68.967