Methylglyoxime

Base Information

• Chemical Name: Methylglyoxime
• CAS No.: 1804-15-5
• Molecular Formula: C3H6N2O2
• Molecular Weight: 102.093
• Hs Code.: 2928000090
• Mol file: 1804-15-5.mol

Synonyms:Glyoxime,methyl- (6CI,7CI);Pyruvaldehyde, dioxime (8CI);Methylglyoxal dioxime;Methylglyoxime;NSC 37378;

Chemical Property of Methylglyoxime

Chemical Property:

• Vapor Pressure: 0.348mmHg at 25°C
• Melting Point: 157 °C
• Refractive Index: 1.486
• Boiling Point: 175.7 °C at 760mmHg
• PKA: 10.44±0.10(Predicted)
• Flash Point: 60.1 °C
• PSA: 65.18000
• Density: 1.22 g/cm³
• LogP: 0.29650
• Water Solubility.: 46g/L(26 oC)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methylglyoxime ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methylglyoxime

There total 26 articles about Methylglyoxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-chloro-1-benzamidoacetone (88297-80-7) → 2-hydroxyimino-propionaldehyde oxime (1804-15-5)

Guidance literature:

With hydroxylamine; sodium acetate; In ethanol; at 90 - 100 ℃; for 4h; pH 7;

DOI:10.1007/BF00954664

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + bis-(hydroxyimino-isopropylidene)-hydrazine → 2-hydroxyimino-propionaldehyde oxime (1804-15-5) + acetone (67-64-1) + propanone 1-oxime (306-44-5)

Guidance literature:

Reference yield:

3-methyl-butan-2-one (563-80-4) + ethyl nitrite (109-95-5) → 2-hydroxyimino-propionaldehyde oxime (1804-15-5) + 3-Methyl-3-nitrosobutan-2-on (6931-05-1,30442-79-6)

Guidance literature:

With hydrogenchloride; at 45 - 55 ℃;

upstream raw materials:

3-methyl-butan-2-one

ethyl nitrite

1,1-Dichloroacetone

1-azidopropan-2-one

Downstream raw materials:

anti-methylphenylglyoxime

methyl-p-tolyl-glyoxime

N-hydroxy-2-(hydroxyimino)propanimidoyl chloride

propylene glycol

Refernces

• 1、 Beirakhov,Orlova,Gorbunova,Mikhailov,Shchelokov. "Uranyl Compounds with α-Dioximes: Mixed-Ligand Carbonatooxalate Complexes". . p. 1414 - 1419. Retrieved 2008/10/08.