1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole

Base Information

• Chemical Name: 1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole
• CAS No.: 1226872-08-7
• Molecular Formula: C₁₇H₁₇N₃O₂
• Molecular Weight: 295.341
• Mol file: 1226872-08-7.mol

Synonyms:1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole

Chemical Property of 1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole

There total 4 articles about 1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-methoxy-4-(2-propynyloxy)benzene (17061-86-8) + benzyl azide (622-79-7) → 1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole (1226872-08-7)

Guidance literature:

With copper(II) acetate monohydrate; copper; In water; at 20 ℃; for 0.583333h; Ultrasound irradiation;

DOI:10.1515/znb-2011-0113

Reference yield: 84.0%

1-methoxy-4-(2-propynyloxy)benzene (17061-86-8) + benzyl azide (622-79-7) → 1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole (1226872-08-7) + 1,4-di[4-methoxyphenoxymethyl]buta-1,3-diyne

Guidance literature:

With Cu₂(OH)3OAc; In acetonitrile; at 100 ℃; for 0.166667h; Microwave irradiation;

DOI:10.1039/b924649e

Reference yield:

1-iodo-2-phenylethyne (932-88-7) + 1-methoxy-4-(2-propynyloxy)benzene (17061-86-8) + benzyl azide (622-79-7) → 1-benzyl-4-phenyl-5-iodo-1,2,3-triazole (860002-66-0) + 1-benzyl-4-phenyl-1H-[1,2,3]triazole (108717-96-0) + 1-(phenylmethyl)-4-methoxy-phenoxymethyl-1H-1,2,3-triazole (1226872-08-7) + 1-benzyl-5-iodo-4-(p-methoxyphenoxymethyl)triazole (1207328-60-6)

Guidance literature:

With copper(I) phenylacetylenide; triethylamine; In tetrahydrofuran; at 20 ℃; for 15h;

DOI:10.1002/chem.201000447

upstream raw materials:

1-iodo-2-phenylethyne

1-methoxy-4-(2-propynyloxy)benzene

benzyl azide

benzyl bromide