Tandospirone citrate

Base Information Edit

Chemical Name:Tandospirone citrate
CAS No.:112457-95-1
Molecular Formula:C21H29N5O2·C6H8O7
Molecular Weight:575.619
Hs Code.:2933990090
UNII:0R8E9BWM4J
Wikidata:Q23702074
NCI Thesaurus Code:C74390
ChEMBL ID:CHEMBL2103888
Mol file:112457-95-1.mol

Synonyms:3a,4,7,7a-hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-4,7-methano-1H-isoindole-1,3(2H)-dione;SM 3997;SM-3997;tandospirone

Suppliers and Price of Tandospirone citrate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Tandospironecitrate 98+%
25mg
$ 194.00

Crysdot
Tandospironecitrate 98+%
10mg
$ 90.00

Crysdot
Tandospironecitrate 98+%
5mg
$ 55.00

ChemScene
Tandospirone(citrate) 98.87%
5mg
$ 96.00

ChemScene
Tandospirone(citrate) 98.87%
10mg
$ 156.00

ChemScene
Tandospirone(citrate) 98.87%
25mg
$ 336.00

American Custom Chemicals Corporation
TANDOSPIRONE CITRATE 95.00%
5MG
$ 503.76

Ambeed
rel-(3aR,4S,7R,7aS)-2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione2-hydroxypropane-1,2,3-tricarboxylate 98+%
25mg
$ 244.00

Ambeed
rel-(3aR,4S,7R,7aS)-2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione2-hydroxypropane-1,2,3-tricarboxylate 98+%
10mg
$ 139.00

Ambeed
rel-(3aR,4S,7R,7aS)-2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione2-hydroxypropane-1,2,3-tricarboxylate 98+%
5mg
$ 86.00

Total 39 raw suppliers

Chemical Property of Tandospirone citrate Edit

Chemical Property:

Vapor Pressure:5.23E-15mmHg at 25°C
Melting Point:169.5-170°
Boiling Point:782.9 °C at 760 mmHg
Flash Point:427.3 °C
PSA：201.77000
LogP:0.10220
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:11
Exact Mass:575.25912777
Heavy Atom Count:41
Complexity:799

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tandospironecitrate 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2CC1C3C2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Isomeric SMILES:C1C[C@H]2C[C@@H]1[C@H]3[C@@H]2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Recent ClinicalTrials:A Based on PEEG and PET Study of Anxiolytic Treatment to Improve Cognitive Function in Patients With Alzheimer Disease
Uses Tandospirone citrate is a potent 5-HT1A partial agonist with a Ki value of 27 nM. Tandospirone citrate is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM). Anti-anxiety agent.

Technology Process of Tandospirone citrate

There total 1 articles about Tandospirone citrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%