(η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph)

Base Information

• Chemical Name: (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph)
• CAS No.: 88994-68-7
• Molecular Formula: C₁₆H₁₆FeO₃
• Molecular Weight: 312.148
• Mol file: 88994-68-7.mol

Synonyms:(η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph)

Chemical Property of (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph)

There total 4 articles about (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

Fe(COC6H4Me-p)(η5-C5H5)(CO)2 + trimethoxonium tetrafluoroborate (420-37-1) → (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph) (88994-68-7)

Guidance literature:

With sodium tetrahydroborate; sodium methylate; In methanol; dichloromethane; Cp(CO)2FeCOC6H4CH3, 2-3 equiv. (CH3)3O(1+)BF4(1-) stirred under N2 in CH2Cl2 (ca. 24h); addn. of this soln. of Cp(CO)2Fe=C(OCH3)C6H4CH3(1+) to a soln. of 2 equiv. NaBH4 and 4equiv. NaOCH3 in CH3OH at -80°C; stirred 15 min; poured in aq. K2CO3; extn. (CH2Cl2); dried (K2CO3), concn.; chromd.; cooling hexane soln. yielded crystals;

DOI:10.1021/om00103a016

Reference yield: 71.0%

(C5H5)Fe(CO)2(CH(OCH3))(1+)*PF6(1-)=[(C5H5)Fe(CO)2(CH(OCH3))]PF6 + p-tolyllithium (2417-95-0) → (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph) (88994-68-7)

Guidance literature:

In diethyl ether; addn. of p-tolyllithium in ether to stirred suspn. of complex in diethyl ether, -78°C, soln. warmed up to room temp., addn. of ethanol, evapn. in vac.; residue extd. with hexane, evapn. of extracts, chromy. (alumina, hexane);

DOI:10.1016/0022-328X(83)80136-3

Reference yield:

K(1+)*(C5H5)Fe(CO)2(CH(C6H4CH3)O)(1-)=K((C5H5)Fe(CO)2(C8H8O)) + methyl iodide (74-88-4) → dicarbonyl(cyclopentadienyl)methyliron(II) + (η(5)-C5H5)(CO)2Fe-CH(OMe)(p-CH3Ph) (88994-68-7)

Guidance literature:

byproducts: [(η(5)-C5H5)(CO)2Fe]2; N2-atmosphere;

DOI:10.1021/om970698y

upstream raw materials:

methyl iodide

trimethoxonium tetrafluoroborate

p-tolyllithium

Downstream raw materials:

trans-1-methyl-2-(4-methylphenyl)cyclopropane

cis-1-methyl-2-p-CH₃-phenylcyclopropane

Cp(CO)2Fe=CH(C₆H₄-p-CH₃)⁽¹⁺⁾

Cp(CO)(Ph₃P)FeCH(OCH₃)(C₆H₄-p-CH₃)

Refernces

• 1、 Theys, Ronald D.,Vargas, Roy M.,Wang, Qinwei,Hossain, M. Mahmun. "A method for the synthesis of carbene precursors from aldehydes and the metalates (η5-C5H5)(CO)2Fe- and (η5-C9H7)(CO)2Fe-". . p. 1333 - 1339. Retrieved 2008/10/08.