[10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester

Base Information

• Chemical Name: [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester
• CAS No.: 388575-15-3
• Molecular Formula: C₂₀H₁₇ClN₄O₄
• Molecular Weight: 412.832

Synonyms:[10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester

Chemical Property of [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester

There total 3 articles about [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

ethyl bromoacetate (105-36-2) + 10-(4-chloro-benzyl)-2,10-dihydro-benzo[4,5]imidazo[2,1-c][1,2,4]triazine-3,4-dione (388575-00-6) → [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester (388575-15-3)

Guidance literature:

With potassium carbonate; In acetone; Heating;

DOI:10.1021/jm0109210

Reference yield:

2-Chloro-1-(p-chlorophenylmethyl)-1H-benzimidazole (131705-80-1) → [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester (388575-15-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / hydrazine hydrate / 5 h / 160 °C

2: 42 percent / ethanol / Heating

3: 73 percent / K₂CO₃ / acetone / Heating

With potassium carbonate; hydrazine hydrate; In ethanol; acetone;

DOI:10.1021/jm0109210

Reference yield:

[1-(4-chloro-benzyl)-1H-benzoimidazol-2-yl]-hydrazine (388574-82-1) → [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester (388575-15-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 42 percent / ethanol / Heating

2: 73 percent / K₂CO₃ / acetone / Heating

With potassium carbonate; In ethanol; acetone;

DOI:10.1021/jm0109210

upstream raw materials:

ethyl bromoacetate

10-(4-chloro-benzyl)-2,10-dihydro-benzo[4,5]imidazo[2,1-c][1,2,4]triazine-3,4-dione

2-Chloro-1-(p-chlorophenylmethyl)-1H-benzimidazole

[1-(4-chloro-benzyl)-1H-benzoimidazol-2-yl]-hydrazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 388575-15-3 [10-(4-chloro-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send