4-DICHLOROMETHYL-4-METHYL-2,5-CYCLOHEXADIENONE

Base Information

• Chemical Name: 4-DICHLOROMETHYL-4-METHYL-2,5-CYCLOHEXADIENONE
• CAS No.: 6611-78-5
• Molecular Formula: C8H8 Cl2 O
• Molecular Weight: 191.057
• Mol file: 6611-78-5.mol

Synonyms:4-Dichloromethyl-4-methyl-2,5-cyclohexadienone;4-Methyl-4-(dichloromethyl)-2,5-cyclohexadien-1-one; 4-Methyl-4-(dichloromethyl)-2,5-cyclohexadienone;NSC 407524

Chemical Property of 4-DICHLOROMETHYL-4-METHYL-2,5-CYCLOHEXADIENONE

Chemical Property:

• Vapor Pressure: 0.00441mmHg at 25°C
• Boiling Point: 277.8°C at 760 mmHg
• Flash Point: 115.5°C
• PSA: 17.07000
• Density: 1.275g/cm³
• LogP: 2.49150

Purity/Quality:

99% ^*data from raw suppliers

4-Dichloromethyl-4-methyl-2,5-cyclohexadienone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-DICHLOROMETHYL-4-METHYL-2,5-CYCLOHEXADIENONE

There total 10 articles about 4-DICHLOROMETHYL-4-METHYL-2,5-CYCLOHEXADIENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

p-cresol (106-44-5) + chloroform (67-66-3,8013-54-5) → 4-dichloromethyl-4-methyl-2,5-cyclohexadienone (6611-78-5) + 2-hydroxy-5-methylbenzaldehyde (613-84-3)

Guidance literature:

With sodium hydroxide; β‐cyclodextrin; In water; at 60 ℃; for 8h;

DOI:10.1021/ja00345a058

Reference yield: 0.2%

p-cresol (106-44-5) + chloroform (67-66-3,8013-54-5) → 4-dichloromethyl-4-methyl-2,5-cyclohexadienone (6611-78-5)

Guidance literature:

at 65 ℃; Reaktion ueber mehrere Stufen;

Reference yield:

p-cresol (106-44-5) + chloroform (67-66-3,8013-54-5) → 4-dichloromethyl-4-methyl-2,5-cyclohexadienone (6611-78-5) + 2-hydroxy-5-methylbenzaldehyde (613-84-3)

Guidance literature:

upstream raw materials:

p-cresol

chloroform

4-methyl-4-(trichloromethyl)cyclohexa-2,5-dien-1-one

ethene

Downstream raw materials:

2,2-dichloro-1-p-tolylethane

4-dichloromethyl-1,4-dimethyl-cyclohexa-2,5-dienol

2-(4-dichloromethyl-1-hydroxy-4-methyl-cyclohexa-2,5-dienyl)-propionic acid

3-methyl-3-chloromethyl-6-isopropylidene-1,4-cyclohexadiene

Refernces

• 1、 Nikanorov, V. A.,Rozenberg, V. I.,Yanovsky, A. I.,Struchkov, Yu. T.,Reutov, O. A.,et al.. "?-CYCLOHEXADIENONE DERIVATIVES OF RHODIUM(I) ACETYLACETONATE. CRYSTAL AND MOLECULAR STRUCTURE OF RHODIUM (η4-4-METHYL-4-exo-TRICHLOROMETHYL-2,5-CYCLOHEXADIENE-1-ONE)(PENTANE-O,O'-2,4-DIONATE)". . p. 363 - 376. Retrieved 1986.
• 2、 -. "Dialkyl-substituted dithianes and pesticidal compositions". . . Retrieved 2008/06/13.