Technology Process of C26H26N4O5
There total 3 articles about C26H26N4O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl 3-(6-amino-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)propanoate;
With
sulfuric acid; sodium nitrite;
In
acetic acid;
at 0 - 20 ℃;
for 3.5h;
2-amino-5-(diethylamino)phenol;
With
acetic acid;
at 0 ℃;
for 1h;
With
sodium acetate;
In
acetic acid;
at 0 - 10 ℃;
for 3h;
DOI:10.1021/bc200424r
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogenchloride; tin(II) chloride dihdyrate / methanol; water / 2 h / Reflux
2.1: sulfuric acid; sodium nitrite / acetic acid / 3.5 h / 0 - 20 °C
2.2: 1 h / 0 °C
2.3: 3 h / 0 - 10 °C
With
hydrogenchloride; tin(II) chloride dihdyrate; sulfuric acid; sodium nitrite;
In
methanol; water; acetic acid;
DOI:10.1021/bc200424r
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ethanol / 3 h / Reflux
2.1: hydrogenchloride; tin(II) chloride dihdyrate / methanol; water / 2 h / Reflux
3.1: sulfuric acid; sodium nitrite / acetic acid / 3.5 h / 0 - 20 °C
3.2: 1 h / 0 °C
3.3: 3 h / 0 - 10 °C
With
hydrogenchloride; tin(II) chloride dihdyrate; sulfuric acid; sodium nitrite;
In
methanol; ethanol; water; acetic acid;
DOI:10.1021/bc200424r