<(4-methoxybenzyl)oxy>tributylstannyl methane

Base Information

• Chemical Name: <(4-methoxybenzyl)oxy>tributylstannyl methane
• CAS No.: 120385-24-2
• Molecular Formula: C₂₁H₃₈O₂Sn
• Molecular Weight: 441.242
• Mol file: 120385-24-2.mol

Synonyms:<(4-methoxybenzyl)oxy>tributylstannyl methane

Chemical Property of <(4-methoxybenzyl)oxy>tributylstannyl methane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <(4-methoxybenzyl)oxy>tributylstannyl methane

There total 2 articles about <(4-methoxybenzyl)oxy>tributylstannyl methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

potassium tert-butylate (865-47-4) + tri-n-butylstannylmethyl iodide (66222-29-5) + 4-Methoxybenzyl alcohol (105-13-5) → <(4-methoxybenzyl)oxy>tributylstannyl methane (120385-24-2)

Guidance literature:

In tetrahydrofuran; to a 0°C soln. of KO-t-Bu in THF was added p-methoxybenzyl alcohol, after 10 min Bu3SnCH2I was added, heating for 5h at 45°C, nitrogen or argon atmosphere; flash chromatographie on silica gel (ether/hexane);

DOI:10.1021/om00109a002

Reference yield: 83.0%

tri-n-butylstannylmethyl iodide (66222-29-5) + 4-Methoxybenzyl alcohol (105-13-5) → <(4-methoxybenzyl)oxy>tributylstannyl methane (120385-24-2)

Guidance literature:

4-Methoxybenzyl alcohol; With potassium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;

tri-n-butylstannylmethyl iodide; In tetrahydrofuran; mineral oil; at 20 ℃; Inert atmosphere;

DOI:10.1039/c8ob01339j

Reference yield: 96.0%

C40H71NO5Si3 (1196801-45-2) + <(4-methoxybenzyl)oxy>tributylstannyl methane (120385-24-2) → C47H76O6Si3 (1196801-46-3)

Guidance literature:

<(4-methoxybenzyl)oxy>tributylstannyl methane; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

C₄₀H₇₁NO₅Si₃; In tetrahydrofuran; hexane; at -78 ℃;

DOI:10.1135/cccc2008181

upstream raw materials:

potassium tert-butylate

tri-n-butylstannylmethyl iodide

4-Methoxybenzyl alcohol

Downstream raw materials:

1-Cyclopent-1-enyl-2-(4-methoxy-benzyloxy)-ethanol

1-(2,2-Dimethyl-6,6a-dihydro-3aH-cyclopenta[1,3]dioxol-4-yl)-2-(4-methoxy-benzyloxy)-ethanol

1-(2-Cyclopent-1-enyl-allyloxymethyl)-4-methoxy-benzene

1-Cyclopent-1-enyl-2-(4-methoxy-benzyloxy)-ethanone

Refernces

• 1、 Ferezou, Jean-Pierre,Julia, Marc,Li, Yun,Liu, Lu Wei,Pancrazi, Ange,Porteu, Florence. "Total synthesis of avermectins, part 1. Enantioselective synthesis of the southern part using a sequential Dieckmann-free radical cyclization approach". . p. 865 - 894. Retrieved 2007/10/02.