5-Benzyl-2,4-diaminopyrimidine

Base Information

• Chemical Name: 5-Benzyl-2,4-diaminopyrimidine
• CAS No.: 7319-45-1
• Molecular Formula: C11H12 N4
• Molecular Weight: 200.243
• Mol file: 7319-45-1.mol

Synonyms:Pyrimidine,2,4-diamino-5-benzyl- (7CI,8CI); 2,4-Diamino-5-benzylpyrimidine; BW 48-224

Chemical Property of 5-Benzyl-2,4-diaminopyrimidine

Chemical Property:

• Vapor Pressure: 1.24E-08mmHg at 25°C
• Boiling Point: 459.7°C at 760 mmHg
• Flash Point: 262.7°C
• PSA: 77.82000
• Density: 1.252g/cm³
• LogP: 2.39420

Purity/Quality:

97% ^*data from raw suppliers

5-BENZYL-2,4-DIAMINOPYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Benzyl-2,4-diaminopyrimidine

There total 12 articles about 5-Benzyl-2,4-diaminopyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-5-benzylpyrimidin-4(3H)-one (873409-32-6) → 2,4-diamino-5-benzylpyrimidine (7319-45-1)

Guidance literature:

With trichlorophosphate; dann mit aethanol.NH₃ auf 155grad;

DOI:10.1021/ja01152a059

Reference yield:

benzaldehyde (100-52-7) → 2,4-diamino-5-benzylpyrimidine (7319-45-1)

Guidance literature:

Multi-step reaction with 3 steps

1: MeONa / dimethylsulfoxide

2: HCl / propan-2-ol / Heating

3: 2.1 g / MeONa / ethanol / 36 h / Heating

With hydrogenchloride; sodium methylate; In ethanol; dimethyl sulfoxide; isopropyl alcohol;

DOI:10.1021/jm030931w

Reference yield:

(E)-2-Benzyl-3-morpholin-4-yl-acrylonitrile (76651-70-2) → 2,4-diamino-5-benzylpyrimidine (7319-45-1)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / propan-2-ol / Heating

2: 2.1 g / MeONa / ethanol / 36 h / Heating

With hydrogenchloride; sodium methylate; In ethanol; isopropyl alcohol;

DOI:10.1021/jm030931w

upstream raw materials:

2-amino-5-benzylpyrimidin-4(3H)-one

5-benzyl-4-chloro-pyrimidin-2-ylamine

5-benzyl-2,4-dichloro-pyrimidine

guanidine hydrochloride

Downstream raw materials:

5-(4-Nitro-benzyl)-pyrimidine-2,4-diamine