<3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Base Information

Chemical Name:<3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester
CAS No.:136386-86-2
Molecular Formula:C₅₈H₅₁F₃N₄O₇S
Molecular Weight:1005.13
Hs Code.:

<3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Synonyms:<3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Suppliers and Price of <3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

There total 10 articles about <3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 113787-89-6
iodoacetyl-L-(S-diphenylmethyl)cysteinyl-D-valine benzhydryl ester

: 136386-85-1
<(3-Hydroxy-5-diphenylmethyloxycarbonyl)phenyl>-3-trifluoromethyl-3H-diazirine

: 136386-86-2
<3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Guidance literature:: With potassium carbonate; In acetone;
DOI:10.1016/S0040-4020(01)80991-1

Reference yield:

: 626-41-5
3,5-dibromophenol

: 136386-86-2
<3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Guidance literature:: Multi-step reaction with 9 steps

1: 81 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / CH₂Cl₂ / 1 h / Ambient temperature

2: 1) BuLi / 1) THF, -78 deg C, 0.5 h; 2) THF, -78 deg C, 0.5 h

3: 81 percent / NH₂OH*HCl, pyridine / ethanol / 4 h / Heating

4: 81 percent / pyridine / 3.5 h / Heating

5: 98 percent / NH₃ / diethyl ether / 8 h / -78 °C

6: 90 percent / RuO₂, NaIO₄ / CCl₄; H₂O; acetonitrile / Ambient temperature

7: 77 percent / 1M aq. LiOH / methanol / 3.5 h

8: 65 percent / acetone / 2 h / Ambient temperature

9: 98 percent / K₂CO₃ / acetone

With pyridine; ruthenium(IV) oxide; lithium hydroxide; sodium periodate; n-butyllithium; hydroxylamine hydrochloride; ammonia; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; tetrachloromethane; diethyl ether; ethanol; dichloromethane; water; acetone; acetonitrile;
DOI:10.1016/S0040-4020(01)80991-1

Reference yield:

: 136386-79-3
(3,5-dibromophenoxy)-tert-butyldimethylsilane

: 136386-86-2
<3-(Diphenylmethyloxycarbonyl)-5-(3-trifluoromethyl-3H-diazirin-3-yl)phenoxy>acetyl-L-(S-diphenylmethyl)cysteinyl-D-valine Diphenylmethyl Ester

Guidance literature:: Multi-step reaction with 8 steps

1: 1) BuLi / 1) THF, -78 deg C, 0.5 h; 2) THF, -78 deg C, 0.5 h

2: 81 percent / NH₂OH*HCl, pyridine / ethanol / 4 h / Heating

3: 81 percent / pyridine / 3.5 h / Heating

4: 98 percent / NH₃ / diethyl ether / 8 h / -78 °C

5: 90 percent / RuO₂, NaIO₄ / CCl₄; H₂O; acetonitrile / Ambient temperature

6: 77 percent / 1M aq. LiOH / methanol / 3.5 h

7: 65 percent / acetone / 2 h / Ambient temperature

8: 98 percent / K₂CO₃ / acetone

With pyridine; ruthenium(IV) oxide; lithium hydroxide; sodium periodate; n-butyllithium; hydroxylamine hydrochloride; ammonia; potassium carbonate; In methanol; tetrachloromethane; diethyl ether; ethanol; water; acetone; acetonitrile;
DOI:10.1016/S0040-4020(01)80991-1