Technology Process of 4-(4-hydroxymethylphenyl)butan-1-ol
There total 6 articles about 4-(4-hydroxymethylphenyl)butan-1-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 20 ℃;
for 6h;
DOI:10.1021/jm0701831
- Guidance literature:
-
With
ethylenediaminetetraacetic acid; dihydrogen peroxide; sodium hydroxide;
In
tetrahydrofuran; water;
at 0 - 20 ℃;
for 0.333333h;
DOI:10.1039/c3cc46727a
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: magnesium; iodine / tetrahydrofuran / 2.02 h / 0 - 20 °C / Inert atmosphere
1.2: 1.03 h / 0 - 20 °C / Inert atmosphere
2.1: sodium tetrahydroborate / ethanol / 2 h / 0 - 20 °C / Inert atmosphere
3.1: 2,6-bis[1-((2,6-diethylphenyl)imino)ethyl]pyridine; para-methylphenylmagnesium bromide; iron(II) chloride / tetrahydrofuran; diethyl ether / 1 h / 20 °C / Inert atmosphere
4.1: sodium hydroxide; dihydrogen peroxide; ethylenediaminetetraacetic acid / tetrahydrofuran; water / 0.33 h / 0 - 20 °C
With
sodium tetrahydroborate; ethylenediaminetetraacetic acid; 2,6-bis[1-((2,6-diethylphenyl)imino)ethyl]pyridine; dihydrogen peroxide; iodine; magnesium; para-methylphenylmagnesium bromide; sodium hydroxide; iron(II) chloride;
In
tetrahydrofuran; diethyl ether; ethanol; water;
DOI:10.1039/c3cc46727a