3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine

Base Information

• Chemical Name: 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine
• CAS No.: 72157-12-1
• Molecular Formula: C₁₆H₁₅N₃
• Molecular Weight: 249.315
• Mol file: 72157-12-1.mol

Synonyms:3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine

Chemical Property of 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine

There total 6 articles about 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

(Z)-3-Phenyl-3-pyridin-3-yl-acrylimidic acid ethyl ester (76132-56-4) + ethylenediamine (107-15-3,85404-18-8) → 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine (72157-12-1)

Guidance literature:

In ethanol; for 2h; Heating;

DOI:10.1248/cpb.28.1394

Reference yield: 68.0%

(Z)-3-Phenyl-3-pyridin-3-yl-acrylimidic acid ethyl ester (344406-22-0) + ethylenediamine (107-15-3,85404-18-8) → 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine (72157-12-1)

Guidance literature:

In ethanol; for 2h; Heating;

DOI:10.1248/cpb.28.1394

Reference yield:

3-Benzoylpyridine (5424-19-1) + (4,5-Dihydro-1H-imidazol-2-ylmethyl)-phosphonic acid diethyl ester (76132-42-8) → 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine (72157-12-1) + 3-[(E)-2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-vinyl]-pyridine (72157-12-1)

Guidance literature:

With sodium ethanolate; In ethanol; for 10h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1248/cpb.28.1394

upstream raw materials:

3-Benzoylpyridine

(4,5-Dihydro-1H-imidazol-2-ylmethyl)-phosphonic acid diethyl ester

(Z)-3-Phenyl-3-pyridin-3-yl-acrylimidic acid ethyl ester

ethylenediamine

Downstream raw materials:

3-[2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenyl-ethyl]-pyridine