cabazitaxel Cbz-β-alanine glycolate

Base Information

Chemical Name:cabazitaxel Cbz-β-alanine glycolate
CAS No.:1308398-71-1
Molecular Formula:C₅₈H₇₀N₂O₁₉
Molecular Weight:1099.2
Hs Code.:

Synonyms:cabazitaxel Cbz-β-alanine glycolate

Suppliers and Price of cabazitaxel Cbz-β-alanine glycolate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of cabazitaxel Cbz-β-alanine glycolate

Chemical Property:

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Technology Process of cabazitaxel Cbz-β-alanine glycolate

There total 4 articles about cabazitaxel Cbz-β-alanine glycolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 183133-96-2,1714967-27-7
carbazitaxel

: 205640-31-9
2-((3-(((benzyloxy)carbonyl)amino)propanoyl)oxy)acetic acid

: 1308398-71-1
cabazitaxel Cbz-β-alanine glycolate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 5h;

Reference yield:

: 183133-96-2,1714967-27-7
carbazitaxel

: 2304-94-1
3-(benzyloxycarbonylamino)propanoic acid

: 1308398-71-1
cabazitaxel Cbz-β-alanine glycolate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 5h; Product distribution / selectivity;

Reference yield:

: 2304-94-1
3-(benzyloxycarbonylamino)propanoic acid

: 1308398-71-1
cabazitaxel Cbz-β-alanine glycolate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 16 h / 60 °C

2: formic acid / 20 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 5 h / 20 °C

With dmap; formic acid; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; acetone;