phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Base Information

• Chemical Name: phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside
• CAS No.: 246513-05-3
• Molecular Formula: C₄₉H₄₆O₈SSi
• Molecular Weight: 823.051
• Mol file: 246513-05-3.mol

Synonyms:phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Chemical Property of phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

There total 3 articles about phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoyl chloride (98-88-4) + phenyl 6-O-(tert-butyl(diphenyl)silyl)-1-thio-β-D-galactopyranoside (195316-81-5) → phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside (246513-05-3)

Guidance literature:

With pyridine; for 10h; Ambient temperature;

DOI:10.1080/07328309708006537

Reference yield:

1-thiophenyl-β-D-galactopyranoside (16758-34-2) → phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside (246513-05-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 16 h / 20 °C

2: 4.95 g / pyridine / 10 h / 20 °C

With pyridine;

DOI:10.1016/S0008-6215(01)00259-2

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-1-thio-β-D-galactopyranoside (246513-05-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 16 h / 20 °C

2: 4.95 g / pyridine / 10 h / 20 °C

With pyridine;

DOI:10.1016/S0008-6215(01)00259-2

upstream raw materials:

benzoyl chloride

phenyl 6-O-(tert-butyl(diphenyl)silyl)-1-thio-β-D-galactopyranoside

1-thiophenyl-β-D-galactopyranoside

tert-butylchlorodiphenylsilane

Downstream raw materials:

6-N-(2,2,2-trichloroethoxycarbonyl)aminohexyl 2,3,4-tri-O-benzoyl-O-(tert-butyldiphenylsilyl)-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

(2R,3aS,4R,6R,7R,7aS)-7-Benzoyloxy-4-benzoyloxymethyl-2-methyl-6-((2R,3S,4S,5R,6S)-3,4,5-tris-benzoyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethoxy)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2-carboxylic acid methyl ester

(2R,3aS,4R,6R,7R,7aS)-7-Benzoyloxy-4-benzoyloxymethyl-2-methyl-6-((2R,3S,4S,5R,6R)-3,4,5-tris-benzoyloxy-6-bromo-tetrahydro-pyran-2-ylmethoxy)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2-carboxylic acid methyl ester

O-(2,3,4-tri-O-benzoyl-6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-(1->4)-2-acetamido-6-O-tert-butyldiphenylsilyl-2-deoxy-β-D-glucopyranosyl azide