(+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate

Base Information

• Chemical Name: (+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate
• CAS No.: 133016-59-8
• Molecular Formula: C₂₁H₂₄FNO₃
• Molecular Weight: 357.425
• Mol file: 133016-59-8.mol

Synonyms:(+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate

Chemical Property of (+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate

There total 1 articles about (+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloroformic acid ethyl ester (541-41-3) + (+/-)-4-[(4-fluorophenyl)phenylmethoxy]-1-methylpiperidine (167108-52-3) → (+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate (133016-59-8)

Guidance literature:

In toluene; Heating;

DOI:10.1248/cpb.42.2276

Reference yield:

(+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate (133016-59-8) → (+/-)-4-[(4-Fluorophenyl)phenylmethoxy]piperidine hydrochloride

Guidance literature:

With sodium hydroxide; In ethanol; water;

Reference yield:

(+/-)-ethyl 4-[(4-fluorophenyl)phenylmethoxy]-1-piperidinecarboxylate (133016-59-8) → 4-[(4-fluorophenyl)phenylmethoxy]piperidine (189346-58-5)

Guidance literature:

With sodium hydroxide; In ethanol; Heating;

DOI:10.1248/cpb.42.2276

upstream raw materials:

chloroformic acid ethyl ester

(+/-)-4-[(4-fluorophenyl)phenylmethoxy]-1-methylpiperidine

Downstream raw materials:

4-[(4-fluorophenyl)phenylmethoxy]piperidine

3-{4-[(4-Fluoro-phenyl)-phenyl-methoxy]-piperidin-1-yl}-propionic acid ethyl ester