25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene

Base Information

• Chemical Name: 25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene
• CAS No.: 1042665-55-3
• Molecular Formula: C₆₂H₈₃IO₅
• Molecular Weight: 1035.24
• Mol file: 1042665-55-3.mol

Synonyms:25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene

Chemical Property of 25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene

There total 3 articles about 25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

p-Iodophenol (540-38-5) + 25-(3-bromopropoxy)-5,11,17,23-tetra-tert-butyl-26,27,28-tripropoxycalix<4>arene (170453-66-4,451502-46-8) → 25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene (1042665-55-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 55 ℃; for 24h;

DOI:10.1080/00397910801982035

Reference yield:

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) → 25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene (1042665-55-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: barium(II) hydroxide; barium(II) oxide / N,N-dimethyl-formamide / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 55 °C / Inert atmosphere

3.2: 24 h / 55 °C / Inert atmosphere

With sodium hydride; barium(II) hydroxide; barium(II) oxide; In N,N-dimethyl-formamide;

DOI:10.3906/kim-1006-693

Reference yield:

tris(propoxy)-4-tert-butylcalix[4]arene (133301-64-1,133813-63-5,133867-68-2,133963-48-1) → 25,26,27-tripropoxy-28-[(3-(4-iodophenoxy)propoxy)]-5,11,17,23-tetra(tert-butyl)calix[4]arene (1042665-55-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 55 °C / Inert atmosphere

2.2: 24 h / 55 °C / Inert atmosphere

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.3906/kim-1006-693

upstream raw materials:

p-Iodophenol

25-(3-bromopropoxy)-5,11,17,23-tetra-tert-butyl-26,27,28-tripropoxycalix<4>arene

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene

tris(propoxy)-4-tert-butylcalix[4]arene