(2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide

Base Information

• Chemical Name: (2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide
• CAS No.: 1118765-37-9
• Molecular Formula: C₂₆H₂₇NO₇
• Molecular Weight: 465.503

Synonyms:(2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide

Chemical Property of (2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide

Chemical Property:

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Technology Process of (2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide

There total 1 articles about (2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-propynamide (7341-96-0) + 4',4''-O,O-dimethylcurcumin (160096-59-3) → (2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide (1118765-37-9)

Guidance literature:

4',4''-O,O-dimethylcurcumin; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.5h;

2-propynamide; In tetrahydrofuran; mineral oil; at 20 ℃; for 24.1667h;

DOI:10.1016/j.bmc.2008.10.057

Reference yield: 84.0%

(2E,6E)-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienamide (1118765-37-9) → (E,E,E)-3-(3,5-bis(3,4-dimethoxystyryl)-1H-pyrazol-4-yl)acrylamide (1118765-44-8)

Guidance literature:

With hydrazine hydrochloride; acetic acid; In ethanol; for 40h; Reflux;

DOI:10.1016/j.bmc.2008.10.057

upstream raw materials:

2-propynamide

4',4''-O,O-dimethylcurcumin

Downstream raw materials:

(E,E,E)-3-(3,5-bis(3,4-dimethoxystyryl)-1H-pyrazol-4-yl)acrylamide

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