Technology Process of C19H17F2N3O4S
There total 5 articles about C19H17F2N3O4S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triethylamine; HATU;
In
acetonitrile;
at 20 - 50 ℃;
for 24h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: acetic acid; nitric acid / 15 °C
1.2: 4 h / 15 - 20 °C
2.1: chlorosulfonic acid / 5 h / 115 °C
3.1: sodium carbonate / tetrahydrofuran; water / 0 - 20 °C
4.1: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 20 °C
5.1: HATU; triethylamine / acetonitrile / 24 h / 20 - 50 °C / Inert atmosphere
With
chlorosulfonic acid; palladium 10% on activated carbon; hydrogen; nitric acid; sodium carbonate; acetic acid; triethylamine; HATU;
In
tetrahydrofuran; methanol; water; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: chlorosulfonic acid / 5 h / 115 °C
2: sodium carbonate / tetrahydrofuran; water / 0 - 20 °C
3: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 20 °C
4: HATU; triethylamine / acetonitrile / 24 h / 20 - 50 °C / Inert atmosphere
With
chlorosulfonic acid; palladium 10% on activated carbon; hydrogen; sodium carbonate; triethylamine; HATU;
In
tetrahydrofuran; methanol; water; acetonitrile;