Technology Process of N-<3-(2-carboxyphenoxy)propyl>-m-hydroxyphenylacetamide
There total 5 articles about N-<3-(2-carboxyphenoxy)propyl>-m-hydroxyphenylacetamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
water;
for 5h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 70 percent / conc. HCl / dioxane / 48 h / Heating
2: 76 percent / thionyl chloride / 0 deg C, 60 deg C, 10 h
3: 65 percent / Et3N, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochoride / acetonitrile; tetrahydrofuran / 24 h / Ambient temperature
4: 83 percent / sodium hydroxide / H2O / 5 h / Ambient temperature
With
hydrogenchloride; sodium hydroxide; thionyl chloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
tetrahydrofuran; 1,4-dioxane; water; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 76 percent / thionyl chloride / 0 deg C, 60 deg C, 10 h
2: 65 percent / Et3N, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochoride / acetonitrile; tetrahydrofuran / 24 h / Ambient temperature
3: 83 percent / sodium hydroxide / H2O / 5 h / Ambient temperature
With
sodium hydroxide; thionyl chloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
tetrahydrofuran; water; acetonitrile;
