115149-46-7 Usage
Uses
Used in Pharmaceutical Industry:
2-[3-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPOXY]-BENZOIC ACID METHYL ESTER is used as a potential drug candidate for its unique structural features that may contribute to specific biological or pharmacological activities. 2-[3-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPOXY]-BENZOIC ACID METHYL ESTER's ability to interact with biological targets could be leveraged to develop new therapeutic agents.
Used in Chemical Synthesis:
In the field of organic chemistry, 2-[3-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPOXY]-BENZOIC ACID METHYL ESTER serves as a starting material for the synthesis of related compounds with desired activities. Its versatile structure allows for modifications that can enhance or alter its biological properties, leading to the creation of a range of novel molecules with potential applications in medicine and biology.
Check Digit Verification of cas no
The CAS Registry Mumber 115149-46-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,1,4 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 115149-46:
(8*1)+(7*1)+(6*5)+(5*1)+(4*4)+(3*9)+(2*4)+(1*6)=107
107 % 10 = 7
So 115149-46-7 is a valid CAS Registry Number.
InChI:InChI=1/C19H17NO5/c1-24-19(23)15-9-4-5-10-16(15)25-12-6-11-20-17(21)13-7-2-3-8-14(13)18(20)22/h2-5,7-10H,6,11-12H2,1H3
115149-46-7Relevant academic research and scientific papers
Synthesis and activities of new arylsulfonamido thromboxane A2 receptor antagonists
Sartori, E.,Camy, F.,Teulon, J. M.,Caussade, F.,Virone-Oddos, A.,Cloarec, A.
, p. 625 - 632 (2007/10/02)
New benzoic, benzeneacetic and thiazole-4-acetic acids bearing an arylsulfonamido alkyl or alkylhetero side chain were synthesized and tested in vitro for affinity for human platelet thromboxane A2 receptors and inhibition of U46619-induced rat aortic ring contraction.Influence of substitution patterns, chain length and presence of heteroatoms were studied and compounds within a 30 nmol range for inhibition of U46619-induced contractions were found.One of the most potent, 2-thiazole-4-acetic acid (VII-4) was orally active (1 mg/kg), as evidenced by the inhibition of U46619-induced platelet aggregation in guinea pigs, ex vivo. thromboxane A2 / receptor antagonist / platelet aggregation / arylsulfonamido derivative
SYNTHESIS OF NOVEL MACROCYCLIC LACTONES WITH POTENTIAL PHARMACOLOGICAL ACTIVITY
Smith, Keith,Morris, Ian K.,Owen, Philip G.,Bass, Robert J.
, p. 77 - 84 (2007/10/02)
The total syntheses of four 14-membered ring lactones, (1a), (2a), (22), and (23), are described.The starting materials are the appropriate 2-hydroxybenzoic or (2-hydroxyphenyl)acetic acids and the final step in each case involves lactonization using a mo