2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone

Base Information

• Chemical Name: 2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone
• CAS No.: 107036-79-3
• Molecular Formula: C₁₅H₁₇N₃O₈
• Molecular Weight: 367.315
• Mol file: 107036-79-3.mol

Synonyms:2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone

Chemical Property of 2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone

There total 5 articles about 2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

2,4-Dinitrofluorobenzene (70-34-8,65727-75-5) + 2-amino-2,3-dideoxy-5,6-O-isopropylidene-L-lyxo-hexonic acid (107036-77-1) → 2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone (107036-79-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h;

DOI:10.1021/jo00382a022

Reference yield:

2-azido-2,3-dideoxy-5,6-O-isopropylidene-L-lyxo-hexono-1,4-lactone (107036-74-8) → 2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone (107036-79-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂, Et₃N / 10percent Pd/C / ethanol; H₂O / 2585.7 Torr

2: 34 percent / K₂CO₃ / dimethylformamide / 3 h / 0 - 20 °C

With hydrogen; potassium carbonate; triethylamine; palladium on activated charcoal; In ethanol; water; N,N-dimethyl-formamide;

DOI:10.1021/jo00382a022

Reference yield:

L-5,6-isopropylidene-gulono-1,4-lactone (56710-46-4,67321-94-2,69602-93-3,100227-29-0,102355-63-5,121357-95-7,94697-68-4) → 2,3-dideoxy-2-<(2,4-dinitrophenyl)amino>-5,6-isopropylidene-L-lyxo-hexono-1,4-lactone (107036-79-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 81 percent / pyridine / 5 h / 0 °C

2: 81 percent / H₂ / 10percent Pd/C / ethyl acetate; H₂O / 2.5 h / 2585.7 Torr

3: 77 percent / NaN₃ / dimethylformamide / 18 h / Ambient temperature

4: H₂, Et₃N / 10percent Pd/C / ethanol; H₂O / 2585.7 Torr

5: 34 percent / K₂CO₃ / dimethylformamide / 3 h / 0 - 20 °C

With pyridine; sodium azide; hydrogen; potassium carbonate; triethylamine; palladium on activated charcoal; In ethanol; water; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jo00382a022

upstream raw materials:

2,4-Dinitrofluorobenzene

2-amino-2,3-dideoxy-5,6-O-isopropylidene-L-lyxo-hexonic acid

L-5,6-isopropylidene-gulono-1,4-lactone

2-azido-2,3-dideoxy-5,6-O-isopropylidene-L-lyxo-hexono-1,4-lactone