3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester

Base Information

• Chemical Name: 3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester
• CAS No.: 181587-50-8
• Molecular Formula: C₁₇H₂₂O₂SSe
• Molecular Weight: 369.386
• Mol file: 181587-50-8.mol

Synonyms:3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester

Chemical Property of 3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester

There total 1 articles about 3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1-ethylthio-1-trimethylsilyl-2-methyl-1-propene (63584-44-1) + γ-phenylselenopropynal diethyl acetal (163189-52-4) → 3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester (181587-50-8)

Guidance literature:

With boron trifluoride diethyl etherate; In 1,2-dichloro-ethane; at -40 ℃; for 1h;

DOI:10.1039/p19960001839

Reference yield: 66.0%

N-butylamine (109-73-9,85404-21-3) + 3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester (181587-50-8) → 3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynoic acid butylamide

Guidance literature:

In benzene; for 48h; Ambient temperature;

DOI:10.1039/p19960001839

Reference yield:

3-Ethoxy-2,2-dimethyl-5-phenylselanyl-pent-4-ynethioic acid S-ethyl ester (181587-50-8) → 1-Butyl-4-ethoxy-3,3-dimethyl-5-[1-phenylselanyl-meth-(Z)-ylidene]-pyrrolidin-2-one

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / benzene / 48 h / Ambient temperature

2: 91 percent / t-BuOK, 18-crown-6 / 2-methyl-propan-2-ol / 0.5 h / Ambient temperature

With 18-crown-6 ether; potassium tert-butylate; In tert-butyl alcohol; benzene;

DOI:10.1039/p19960001839

upstream raw materials:

1-ethylthio-1-trimethylsilyl-2-methyl-1-propene

γ-phenylselenopropynal diethyl acetal