2-(2-Chloro-3-nitrophenyl)acetonitrile

Base Information

Chemical Name:2-(2-Chloro-3-nitrophenyl)acetonitrile
CAS No.:108772-95-8
Molecular Formula:C₈H₅ClN₂O₂
Molecular Weight:196.593
Hs Code.:
DSSTox Substance ID:DTXSID201295105

Synonyms:2-(2-chloro-3-nitrophenyl)acetonitrile;108772-95-8;SCHEMBL10867768;DTXSID201295105;2-Chloro-3-nitrobenzeneacetonitrile;(2-chloro-3-nitrophenyl)acetonitrile;F85840

Suppliers and Price of 2-(2-Chloro-3-nitrophenyl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 2-(2-Chloro-3-nitrophenyl)acetonitrile

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:196.0039551
Heavy Atom Count:13
Complexity:242

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)[N+](=O)[O-])Cl)CC#N

Technology Process of 2-(2-Chloro-3-nitrophenyl)acetonitrile

There total 3 articles about 2-(2-Chloro-3-nitrophenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 143-33-9,25596-52-5
sodium cyanide

: 108772-93-6
2-chloro-3-nitrobenzyl chloride

: 108772-95-8
2-chloro-3-nitrophenylacetonitrile

: 108772-94-7
2,3-Bis-(2-chloro-3-nitro-phenyl)-propionitrile

Guidance literature:: With tetrabutylammomium bromide; In dichloromethane; water; for 18h; Ambient temperature;
DOI:10.1021/jm00390a009

Reference yield:

: 89639-98-5
(2-chloro-3-nitrophenyl)methanol

: 108772-95-8
2-chloro-3-nitrophenylacetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂, pyridine / toluene / 5 h / 45 - 50 °C

2: dimethylsulfoxide / 0.5 h / Ambient temperature

With pyridine; thionyl chloride; In dimethyl sulfoxide; toluene;
DOI:10.1021/jm00390a009

Reference yield:

: 3970-35-2
2-chloro-3-nitrobezoic acid

: 108772-95-8
2-chloro-3-nitrophenylacetonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / B₂H₆ / tetrahydrofuran

2: SOCl₂, pyridine / toluene / 5 h / 45 - 50 °C

3: dimethylsulfoxide / 0.5 h / Ambient temperature

With pyridine; thionyl chloride; diborane; In tetrahydrofuran; dimethyl sulfoxide; toluene;
DOI:10.1021/jm00390a009