2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid

Base Information

Chemical Name:2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid
CAS No.:913689-08-4
Molecular Formula:C₂₀H₁₀F₂O₅
Molecular Weight:368.293
Hs Code.:
DSSTox Substance ID:DTXSID901176465
Nikkaji Number:J902.957E
Wikidata:Q27123366
Mol file:913689-08-4.mol

Synonyms:2-(2,7-difluoro-3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid

Suppliers and Price of 2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoicAcid
25mg
$ 165.00

Medical Isotopes, Inc.
2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoicAcid
250 mg
$ 2200.00

Medical Isotopes, Inc.
2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoicAcid
25 mg
$ 650.00

Total 3 raw suppliers

Chemical Property of 2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:368.04962974
Heavy Atom Count:27
Complexity:768

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=C3C=C(C(=O)C=C3OC4=CC(=C(C=C42)F)O)F)C(=O)O
Uses 2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid, is an intermediate used for the synthesis of 4',5'-Bis(1,3,2-dithiarsolan-2-yl)-2',7'-difluoro-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one (B431935), a fluorinated biarsenical derivatives, used as probes. 2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid, is an intermediate used for the synthesis of 4'',5''-Bis(1,3,2-dithiarsolan-2-yl)-2'',7''-difluoro-3'',6''-dihydroxyspiro[isobenzofuran-1(3H),9''-[9H]xanthen]-3-one (B431935), a fluorinated biarsenical derivatives, used as probes.

Technology Process of 2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid

There total 9 articles about 2-(2,7-Difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 85-44-9
phthalic anhydride

: 103068-41-3
4-fluororesorcinol

: 913689-08-4
2-(2,7-difluoro-3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid

Guidance literature:: With methanesulfonic acid; at 60 ℃; for 15h;
DOI:10.1039/c4ob02256d

Reference yield: 75.0%

: 913689-08-4
2-(2,7-difluoro-3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid

Guidance literature:: With methanesulfonic acid; at 100 ℃; for 24h;

Reference yield:

: 195136-58-4
2′,7′-difluorofluorescein

: 913689-08-4
2-(2,7-difluoro-3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / 2,6-lutidine / CH₂Cl₂ / 20 °C

2: aq. hypoxanthine; xanthine oxidase / dimethylsulfoxide; various solvent(s) / 37 °C / pH 7.4

With 2,6-dimethylpyridine; 1,7-dihydro-6H-purin-6-one; xanthine oxidase; In dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ja047018k