12N-4-methoxybenzyl matrinic acid

Base Information

• Chemical Name: 12N-4-methoxybenzyl matrinic acid
• CAS No.: 1331769-88-0
• Molecular Formula: C₂₃H₃₄N₂O₃
• Molecular Weight: 386.535
• Mol file: 1331769-88-0.mol

Synonyms:12N-4-methoxybenzyl matrinic acid

Chemical Property of 12N-4-methoxybenzyl matrinic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 12N-4-methoxybenzyl matrinic acid

There total 5 articles about 12N-4-methoxybenzyl matrinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C36H44N2O3 → 12N-4-methoxybenzyl matrinic acid (1331769-88-0)

Guidance literature:

With 3-methyl-phenol; at 80 ℃;

DOI:10.1016/j.bmcl.2011.06.071

Reference yield:

(+)-matrine (519-02-8) → 12N-4-methoxybenzyl matrinic acid (1331769-88-0)

Guidance literature:

Multi-step reaction with 4 steps

1: water; potassium hydroxide / 9 h / Reflux

2: methanol; Petroleum ether

3: potassium carbonate / dichloromethane / 20 °C

4: 3-methyl-phenol / 80 °C

With water; potassium carbonate; 3-methyl-phenol; potassium hydroxide; In methanol; dichloromethane; Petroleum ether;

DOI:10.1016/j.bmcl.2011.06.071

Reference yield:

matrinic acid diphenylmethyl ester (1331769-92-6) → 12N-4-methoxybenzyl matrinic acid (1331769-88-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / dichloromethane / 20 °C

2: 3-methyl-phenol / 80 °C

With potassium carbonate; 3-methyl-phenol; In dichloromethane;

DOI:10.1016/j.bmcl.2011.06.071

upstream raw materials:

matrinic acid diphenylmethyl ester

(+)-matrine

matrinic acid

Downstream raw materials:

C₂₃H₃₆N₂O₂