4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid

Base Information

• Chemical Name: 4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid
• CAS No.: 1323432-95-6
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 174.094
• Mol file: 1323432-95-6.mol

Synonyms:4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid

Chemical Property of 4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid

There total 2 articles about 4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-oxo-4-(phenyl-13C6)butanoic-1,2,3,4-13C4 acid (1323432-93-4,1346600-75-6) → 4-(phenyl-13C6)butanoic-1,2,3,4-13C4 acid (1323432-95-6)

Guidance literature:

4-oxo-4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid; With hydrazine hydrate; In diethylene glycol; at 20 ℃; for 0.5h;

With potassium hydroxide; In diethylene glycol; at 120 - 215 ℃;

DOI:10.1039/c0ob01107j

Reference yield:

benzene-(13)C6 (32488-44-1) → 4-(phenyl-13C6)butanoic-1,2,3,4-13C4 acid (1323432-95-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: aluminum (III) chloride / 1,1,2,2-tetrachloroethane

2.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C

2.2: 120 - 215 °C

With aluminum (III) chloride; hydrazine hydrate; In 1,1,2,2-tetrachloroethane; diethylene glycol; 2.1: Wolff-Kishner reduction / 2.2: Wolff-Kishner reduction;

DOI:10.1039/c0ob01107j

Reference yield: 95.0%

4-(phenyl-13C6)butanoic-1,2,3,4-13C4 acid (1323432-95-6) → 3,4-dihydronaphthalen-1(2H)-one-13C10 (1323432-59-2,189811-58-3)

Guidance literature:

With methanesulfonic acid; at 90 ℃; for 0.5h; Inert atmosphere;

DOI:10.1039/c0ob01107j

upstream raw materials:

4-oxo-4-(phenyl-¹³C₆)butanoic-1,2,3,4-¹³C₄ acid

benzene-⁽¹³⁾C₆

Downstream raw materials:

U-⁽¹³⁾C-naphthalene

U-(13)C-phenanthrene

U-(13)C-pyrene

U-⁽¹³⁾C-phthalic acid

Refernces

• 1、 Zhang, Zhenfa,Sangaiah, Ramiah,Gold, Avram,Ball, Louise M.. "Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons". supporting information; experimental part. p. 5431 - 5435. Retrieved 2011/09/14.