N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Base Information

• Chemical Name: N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide
• CAS No.: 111986-20-0
• Molecular Formula: C₁₉H₁₄BrN₅O₅
• Molecular Weight: 472.255

Synonyms:N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Chemical Property of N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

There total 4 articles about N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Nitrobenzoyl isocyanate (5843-48-1) + 4-(5-bromo-2-pyrimidinyloxy)-3-methylaniline (111986-57-3) → N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide (111986-20-0)

Guidance literature:

In 1,4-dioxane; Ambient temperature;

DOI:10.1248/cpb.39.2308

Reference yield:

2-nitrobenzamide (610-15-1) + 4-(5-bromo-2-pyrimidinyloxy)-3-methylphenyl isocyanate (111986-79-9) → N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide (111986-20-0)

Guidance literature:

In methanol; toluene;

Reference yield:

4-amino-2-methylphenol (2835-96-3) → N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide (111986-20-0)

Guidance literature:

Multi-step reaction with 2 steps

2: dioxane / Ambient temperature

In 1,4-dioxane;

DOI:10.1248/cpb.39.2308

upstream raw materials:

2-Nitrobenzoyl isocyanate

4-(5-bromo-2-pyrimidinyloxy)-3-methylaniline

4-amino-2-methylphenol

2-nitrobenzamide

Downstream raw materials:

[1-(2-{3-[4-(5-bromo-pyrimidin-2-yloxy)-3-methyl-phenyl]-ureidocarbonyl}-phenylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester

[(2-{3-[4-(5-bromo-pyrimidin-2-yloxy)-3-methyl-phenyl]-ureidocarbonyl}-phenylcarbamoyl)-methyl]-carbamic acid tert-butyl ester

2-amino-N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 111986-20-0 N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send