tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

Base Information

Chemical Name:tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate
CAS No.:1231672-20-0
Molecular Formula:C₁₁H₂₀INO₃
Molecular Weight:341.189
Hs Code.:

Synonyms:tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

Suppliers and Price of tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
(R)-N-Boc-4-(iodomethyl)-2,2-dimethyloxazolidine
1g
$ 1268.00

Total 2 raw suppliers

Chemical Property of tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(R)-N-Boc-4-(iodomethyl)-2,2-dimethyloxazolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

There total 5 articles about tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 108149-63-9,108149-65-1
tert-butyl (4S)-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

: 1231672-20-0
tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

Guidance literature:: With 1H-imidazole; iodine; triphenylphosphine; In toluene; at 20 ℃; for 24h;
DOI:10.3998/ark.5550190.0011.910

Reference yield:

: 136703-59-8
(3S)-3-[(tert-butoxycarbonyl)amino]-4-hydroxybutanoic acid methyl ester

: 1231672-20-0
tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: boron trifluoride diethyl etherate / acetone

2: diisobutylaluminium hydride / toluene / -78 °C

3: 1H-imidazole; iodine; triphenylphosphine / toluene / 5 h / 20 °C

With 1H-imidazole; boron trifluoride diethyl etherate; iodine; diisobutylaluminium hydride; triphenylphosphine; In acetone; toluene;
DOI:10.1039/c4md00136b

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1231672-20-0
tert-butyl [(4R)-2,2-dimethyl-4-(iodomethyl)-1,3-oxazolidin-3-yl]carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydroxide / tert-butyl alcohol; water

2: potassium carbonate / N,N-dimethyl-formamide

3: boron trifluoride diethyl etherate / acetone

4: diisobutylaluminium hydride / toluene / -78 °C

5: 1H-imidazole; iodine; triphenylphosphine / toluene / 5 h / 20 °C

With 1H-imidazole; boron trifluoride diethyl etherate; iodine; diisobutylaluminium hydride; potassium carbonate; triphenylphosphine; sodium hydroxide; In water; N,N-dimethyl-formamide; acetone; toluene; tert-butyl alcohol;
DOI:10.1039/c4md00136b