C₁₆H₂₅FOSi₂

Base Information

• Chemical Name: C₁₆H₂₅FOSi₂
• CAS No.: 1379534-72-1
• Molecular Formula: C₁₆H₂₅FOSi₂
• Molecular Weight: 308.543
• Mol file: 1379534-72-1.mol

Synonyms:C₁₆H₂₅FOSi₂

Chemical Property of C₁₆H₂₅FOSi₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₅FOSi₂

There total 5 articles about C₁₆H₂₅FOSi₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H23Cl2FOSi2 → C16H25FOSi2 (1379534-72-1)

Guidance literature:

With ammonium chloride; In methanol; at 20 ℃; for 3h;

DOI:10.1021/ol301280u

Reference yield:

1-(2′-bromo-5′-fluorophenyl)ethan-1-ol (906673-56-1) → C16H25FOSi2 (1379534-72-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: manganese(IV) oxide / dichloromethane / 5 h / Reflux

2.1: potassium tert-butylate / tetrahydrofuran / 3 h / 20 °C

3.1: N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium / diethyl ether / 0.5 h / -78 °C

3.2: 1 h / 20 °C

4.1: zinc-copper couple / 1,2-dimethoxyethane; diethyl ether / 12 h / 20 °C

5.1: ammonium chloride / methanol / 3 h / 20 °C

With manganese(IV) oxide; N,N,N,N,-tetramethylethylenediamine; potassium tert-butylate; tert.-butyl lithium; ammonium chloride; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether; dichloromethane;

DOI:10.1021/ol301280u

Reference yield:

C14H23FSi2 → C16H25FOSi2 (1379534-72-1)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc-copper couple / 1,2-dimethoxyethane; diethyl ether / 12 h / 20 °C

2: ammonium chloride / methanol / 3 h / 20 °C

With ammonium chloride; In methanol; 1,2-dimethoxyethane; diethyl ether;

DOI:10.1021/ol301280u

upstream raw materials:

1-(2′-bromo-5′-fluorophenyl)ethan-1-ol

1-(2′-bromo-5′-fluorophenyl)ethan-1-one