906673-56-1

Basic information

• Product Name: 1-(2-bromo-5-fluorophenyl)ethanol
• Synonyms: 1-(2-bromo-5-fluorophenyl)ethanol;1-(2-BROMO-5-FLUOROPHENYL)ETHANOL(WXFC0450)
• CAS NO: 906673-56-1
• Molecular Formula: C₈H₈BrFO
• Molecular Weight: 219.0509232
• Mol File: 906673-56-1.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-bromo-5-fluorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-bromo-5-fluorophenyl)ethanol(906673-56-1)
• EPA Substance Registry System: 1-(2-bromo-5-fluorophenyl)ethanol(906673-56-1)

Safety Data

• Hazardous Substances Data: 906673-56-1(Hazardous Substances Data)

Usage

General Description

1-(2-bromo-5-fluorophenyl)ethanol is a chemical compound with the molecular formula C8H8BrFO. It is a colorless to pale yellow liquid that is commonly used as an intermediate for the production of pharmaceuticals and agrochemicals. 1-(2-bromo-5-fluorophenyl)ethanol is known for its antibacterial and antifungal properties, making it a valuable component in the development of new drugs and pesticides. Its chemical structure consists of a phenol ring with a fluorine and bromine substituent, as well as an ethyl group attached to the hydroxyl group. 1-(2-bromo-5-fluorophenyl)ethanol is a potentially hazardous chemical and should be handled and stored with care.

Upstream product

• 94569-84-3 2-bromo-5-fluorobenzaldehyde 
• 1006-33-3 1-(2′-bromo-5′-fluorophenyl)ethan-1-one 
• 676-58-4 methylmagnesium chloride 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1006-33-3 1-(2′-bromo-5′-fluorophenyl)ethan-1-one 
• 1379534-72-1 C₁₆H₂₅FOSi₂ 
• 1350844-26-6 1-(5-fluoro-2-(pent-1-ynyl)phenyl)ethanone 
• 905710-67-0 2-bromo-5-fluoro-[1-(methoxymethoxy)ethyl]benzene 

Relevant articles and documents

The intramolecular reaction of acetophenoneN-tosylhydrazone and vinyl: Br?nsted acid-promoted cationic cyclization toward polysubstituted indenes

In the presence of TsNHNH2, a Br?nsted acid-promoted intramolecular cyclization ofo-(1-arylvinyl) acetophenone derivatives was developed, leading to polysubstituted indenes with complexity and diversity in moderate to excellent yields. In sharp contrast with either the radical or carbene involved cyclization of aldehydicN-tosylhydrazone with vinyl, a cationic cyclization pathway was involved, whereN-tosylhydrazone served as an electrophile and alkylation reagent during this transformation.

Asymmetric Synthesis and Application of Chiral Spirosilabiindanes

Reported here is the development of a class of chiral spirosilabiindane scaffolds by Rh-catalyzed asymmetric double hydrosilation, for the first time. Enantiopure SPSiOL (spirosilabiindane diol), a new type of chiral building block for the preparation of various chiral ligands and catalysts, was readily prepared on greater than 10 gram scale using this protocol. The potential of this new spirosilabiindane scaffold in asymmetric catalysis was preliminarily demonstrated by development of the corresponding monodentate phosphoramidite ligands (SPSiPhos), which were used in both a Rh-catalyzed hydrogenation and a Pd-catalyzed intramolecular carboamination.

Synthesis of fluorenyl alcohols: Via cooperative palladium/norbornene catalysis

Herein, we report a novel catalytic synthesis of substituted 9H-fluoren-9-ols starting from aryl iodides and secondary ortho-bromobenzyl alcohols in the presence of palladium/norbornene as a catalytic system. The present protocol exhibits high functional