Technology Process of 1D-(1,3/2,4)-4-acetoxymethyl-3-O-acetyl-2-O-benzoyl-5-cyclohexene-1,2,3-triol
There total 8 articles about 1D-(1,3/2,4)-4-acetoxymethyl-3-O-acetyl-2-O-benzoyl-5-cyclohexene-1,2,3-triol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate; cerium(III) chloride;
In
ethanol; dichloromethane;
at -78 ℃;
DOI:10.1246/cl.1994.37
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 82 percent / LDA / tetrahydrofuran / -78 °C
2: 82 percent / NaBH4 / dimethylsulfoxide / 80 °C
3: 100 percent / pyridine / Ambient temperature
4: NBS, BaCO3 / CCl4 / Heating
5: NaI / acetone / Heating
6: DBU, MS-4A / dimethylsulfoxide / 1 h / 80 °C
7: 1.) HgCl2, 2.) Et3N / 1.) acetone-H2O, reflux, 1 h, 2.) CH2Cl2, 0 deg C
8: 67 percent / NaBH4, CeCl3*7H2O / ethanol; CH2Cl2 / -78 °C
With
pyridine; sodium tetrahydroborate; N-Bromosuccinimide; cerium(III) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; barium carbonate; sodium iodide; mercury dichloride; lithium diisopropyl amide;
In
tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane; dimethyl sulfoxide; acetone;
DOI:10.1246/cl.1994.37
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 100 percent / pyridine / Ambient temperature
2: NBS, BaCO3 / CCl4 / Heating
3: NaI / acetone / Heating
4: DBU, MS-4A / dimethylsulfoxide / 1 h / 80 °C
5: 1.) HgCl2, 2.) Et3N / 1.) acetone-H2O, reflux, 1 h, 2.) CH2Cl2, 0 deg C
6: 67 percent / NaBH4, CeCl3*7H2O / ethanol; CH2Cl2 / -78 °C
With
pyridine; sodium tetrahydroborate; N-Bromosuccinimide; cerium(III) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; barium carbonate; sodium iodide; mercury dichloride;
In
tetrachloromethane; ethanol; dichloromethane; dimethyl sulfoxide; acetone;
DOI:10.1246/cl.1994.37
