Technology Process of C25H21FN2O4
There total 8 articles about C25H21FN2O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C26H23FN2O4;
With
methanol; lithium hydroxide; water;
In
tetrahydrofuran;
at 65 ℃;
for 3h;
With
hydrogenchloride; water;
In
tetrahydrofuran; methanol;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: tetrahydrofuran / 5.5 h / -20 - 5 °C
2: xylenes / 0.17 h / 160 °C
3: N-iodo-succinimide / tetrahydrofuran / 0.42 h / -78 °C
4: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; water / 1 h / 85 °C
5: caesium carbonate / tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 1 h / 0 °C
6: methanol; lithium hydroxide; water / tetrahydrofuran / 3 h / 65 °C
With
methanol; lithium hydroxide; N-iodo-succinimide; water; potassium carbonate; caesium carbonate;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; xylenes;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-iodo-succinimide / tetrahydrofuran / 0.42 h / -78 °C
2: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; water / 1 h / 85 °C
3: caesium carbonate / tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 1 h / 0 °C
4: methanol; lithium hydroxide; water / tetrahydrofuran / 3 h / 65 °C
With
methanol; lithium hydroxide; N-iodo-succinimide; water; potassium carbonate; caesium carbonate;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;