Technology Process of 4-(1-phenyl-1H-tetrazol-5-sulfonyl)butyric acid benzyl ester
There total 4 articles about 4-(1-phenyl-1H-tetrazol-5-sulfonyl)butyric acid benzyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 20 ℃;
for 16h;
Inert atmosphere;
DOI:10.1080/00397911.2011.635394
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dimethylsulfide borane complex / tetrahydrofuran / 20 °C / Cooling with ice; Inert atmosphere
2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 2 h / 0 °C / Inert atmosphere
3: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 20 °C / Inert atmosphere
With
dimethylsulfide borane complex; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; toluene;
2: |Mitsunobu Displacement;
DOI:10.1080/00397911.2011.635394
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 2 h / 0 °C / Inert atmosphere
2: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 20 °C / Inert atmosphere
With
sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; toluene;
1: |Mitsunobu Displacement;
DOI:10.1080/00397911.2011.635394
