91970-62-6

Basic information

• Product Name: Butanoic acid, 4-hydroxy-, phenylmethyl ester
• CAS NO: 91970-62-6
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 91970-62-6.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4-hydroxy-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-hydroxy-, phenylmethyl ester(91970-62-6)
• EPA Substance Registry System: Butanoic acid, 4-hydroxy-, phenylmethyl ester(91970-62-6)

Safety Data

• Hazardous Substances Data: 91970-62-6(Hazardous Substances Data)

Upstream product

• 96-48-0 4-butanolide 
• 20194-18-7 sodium phenyl-methanolate 
• 86170-45-8 benzyl 3-butenoate 
• 502-85-2 sodium 4-hydroxybutanoate 
• 100-39-0 benzyl bromide 
• 591-81-1 4-hydroxybutanoic acid 
• 100-44-7 benzyl chloride 
• 103-40-2 succinic acid monobenzyl ester 
• 100-51-6 benzyl alcohol 

Downstream Products

• 143528-04-5 3-(Benzyloxycarbonyl)propyl 2,3,4,6-tetra-O-benzyl-β-D-mannopyranoside 
• 134879-38-2 4-oxo-4-(phenylmethoxy)butyl (4S,5R)-4-(cyclohexylmethyl)-2,2-dimethyl-3-<(1,1-dimethylethoxy)carbonyl>-5-oxazolidinecarboxylate 
• 159379-36-9 3-(benzyloxycarbonyl)propyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside 
• 218607-07-9 3-(benzyloxycarbonyl)propyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 214543-61-0 chloromethyl (3-benzyloxycarbonylpropyl) carbonate 
• 1427219-14-4 4-(1-phenyl-1H-tetrazol-5-sulfonyl)butyric acid benzyl ester 
• 1427219-16-6 (6R)-9-benzyloxy-6-methylnon-4-enoic acid benzyl ester 
• 1427219-17-7 (6R)-9-benzyloxy-6-methylnon-4-enoic acid benzyl ester 
• 1427219-13-3 4-(1-phenyl-1H-tetrazol-5-ylsulfanyl)butyric acid benzyl ester 
• 143528-19-2 3-(Benzyloxycarbonyl)propyl 2,3,4-tri-O-acetyl-β-L-fucopyranoside 
• 96-48-0 4-butanolide 
• 347391-76-8 3-benzyloxycarbonylamino-1-propyl 2-deoxy-2-phthalimido-β-D-glucopyranoside 

Relevant articles and documents

Di-(benzimidazole)-1, 2, 3-triazole derivative as well as preparation and application thereof in inflammatory dermatosis

The invention belongs to the technical field of drug small molecules, and particularly discloses a brand-new di-(benzimidazole)-1, 2, 3-triazole derivative as well as preparation and application of the brand-new di-(benzimidazole)-1, 2, 3-triazole derivative. The research finds that the brand new compound has an excellent drug effect and low toxic and side effects on the aspect of inflammatory dermatosis, and has a good application prospect in the aspect of drug development of the inflammatory dermatosis.

A NEW TEMPLATE of MITSUNOBU ACYLATE CLEAVABLE in NONALKALINE CONDITIONS

The Mitsunobu inversion is one of the reliable methods for stereospecific substitution of chiral alcohols, but its deacylation step has limited the substrate scope. Here, we propose a new template of the Mitsunobu acylate that can be deacylated in non-alkaline treatments. The 3,4-dihydroxy-2-methylenebutanoate was selected as a template structure, and its acetonide- or bisTBS derivatives were synthesized. The latter especially showed excellent inversion efficiency (up to >99% ee) and good elimination performance for a series of secondary alcohols in near-neutral conditions. The results demonstrated the applicability of the new template for the substrates labile in alkaline conditions, such as a-hydroxyesters.

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