2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene

Base Information

• Chemical Name: 2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene
• CAS No.: 1160994-77-3
• Molecular Formula: C₂₅H₃₀BF₂N₃O
• Molecular Weight: 437.341
• Mol file: 1160994-77-3.mol

Synonyms:2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene

Chemical Property of 2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene

There total 2 articles about 2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

acetyl chloride (75-36-5) + 10-(4-aminophenyl)-2,8-diethyl-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2′,1′-f ]-[1,3,2]diazaborinin-4-ium-5-uide → 2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene (1160994-77-3)

Guidance literature:

In dichloromethane; at 25 ℃; for 12h;

DOI:10.1002/chem.201602354

Reference yield:

2,8-diethyl-5,5-difluoro-1,3,7,9-tetramethyl-10-(4-nitrophenyl)-dipyrrolo[1,2-c:2,1-f][1,3,2]diazaborinin-4-ium-5-uide → 2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-(4’-N-acetylaminophenyl)-4-bora-3a,4a-diaza-s-indecene (1160994-77-3)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium on carbon / ethanol; water / 24 h / 70 °C

2: dichloromethane / 12 h / 25 °C

With palladium on carbon; In ethanol; dichloromethane; water;

DOI:10.1002/chem.201602354

upstream raw materials:

acetyl chloride