Benzene,1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-

Base Information

Chemical Name:Benzene,1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-
CAS No.:158959-32-1
Molecular Formula:C18H17 F O2 S
Molecular Weight:316.396
Hs Code.:
Mol file:158959-32-1.mol

Synonyms:1-Fluoro-4-[2-(4-methylsulfonylphenyl)-1-cyclopenten-1-yl]benzene;1-[2-(4-Fluorophenyl)cyclopenten-1-yl]-4-(methylsulfonyl)benzene; SC 57666

Suppliers and Price of Benzene,1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
SC57666 98.94%
20mg
$ 2400.00

ChemScene
SC57666 98.94%
10mg
$ 1392.00

ChemScene
SC57666 98.94%
5mg
$ 768.00

ChemScene
SC57666 98.94%
1mg
$ 384.00

Total 4 raw suppliers

Chemical Property of Benzene,1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-

Chemical Property:

PSA：42.52000
LogP:5.40470

Purity/Quality:

97% ^*data from raw suppliers

SC57666 98.94% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzene,1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-

There total 8 articles about Benzene,1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1765-93-1
4-fluoroboronic acid

: 158959-73-0
1-(2-bromocyclopenten-1-yl)-4-(methylsulfonyl)benzene

: 158959-32-1
1-(2-(4-fluorophenyl)cyclopenten-1-yl)-4-(methylsulfonyl)benzenee

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In toluene; Heating;
DOI:10.1021/jm00049a005

Reference yield: 54.0%

: 158959-65-0
1-<2-(4-fluorophenyl)cyclopenten-1-yl>-4-(methylthio)benzene

: 158959-32-1
1-(2-(4-fluorophenyl)cyclopenten-1-yl)-4-(methylsulfonyl)benzenee

Guidance literature:: With Oxone; In tetrahydrofuran; methanol; water; for 4h;
DOI:10.1021/jm00022a023

Reference yield:

: 75415-78-0
1,2-dibromocyclopentene

: 158959-32-1
1-(2-(4-fluorophenyl)cyclopenten-1-yl)-4-(methylsulfonyl)benzenee

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / Cs₂CO₃ / PdCl₂(PPh₃)2 / dimethylformamide / 100 °C

2: 69 percent / aq. Na₂CO₃ / Pd(PPh₃)4 / toluene; ethanol / Heating

With sodium carbonate; caesium carbonate; bis-triphenylphosphine-palladium(II) chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; N,N-dimethyl-formamide; toluene; 1: Suzuki cross-coupling reaction / 2: Suzuki cross-coupling reaction;
DOI:10.1039/b412871k