2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one

Base Information

• Chemical Name: 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one
• CAS No.: 124909-80-4
• Molecular Formula: C₃₃H₃₀O₈
• Molecular Weight: 554.596
• Mol file: 124909-80-4.mol

Synonyms:2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one

Chemical Property of 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one

There total 2 articles about 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-(3,4-bis-benzyloxy-phenyl)-3-hydroxy-5,6,7-trimethoxy-chromen-4-one (52378-73-1) + dimethyl sulfate (77-78-1) → 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one (124909-80-4)

Guidance literature:

With potassium carbonate; In acetone; Reflux;

DOI:10.1021/np800423j

Reference yield:

3,4-bis-benzyloxy-benzoic acid-anhydride (1592-48-9) + 1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone (14639-73-7) + dimethyl sulfate (77-78-1) → 2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one (124909-80-4)

Guidance literature:

With Potassium benzoate; potassium carbonate; Multistep reaction; 1.) 170/180 deg C, 8 h, 2.) acetone, reflux, 2.5-4 h;

Reference yield: 91.0%

2-(3,4-Bis-benzyloxy-phenyl)-3,5,6,7-tetramethoxy-chromen-4-one (124909-80-4) → 2-(3,4-Bis-benzyloxy-phenyl)-5-hydroxy-3,6,7-trimethoxy-chromen-4-one (24160-94-9)

Guidance literature:

With aluminum tri-bromide; In acetonitrile; at 0 ℃;

DOI:10.1021/np800423j

upstream raw materials:

3,4-bis-benzyloxy-benzoic acid-anhydride

1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone

dimethyl sulfate

2-(3,4-bis-benzyloxy-phenyl)-3-hydroxy-5,6,7-trimethoxy-chromen-4-one

Downstream raw materials:

2-(3,4-Bis-benzyloxy-phenyl)-5-hydroxy-3,6,7-trimethoxy-chromen-4-one

3′-dimethoxy-5,6,4′-trihydroxyflavon

3,3',4',5-Tetraacetoxy-6,7-dimethoxyflavon

3',4'-bis(benzyloxy)-3-hydroxy-6,7-dimethoxy-5-(tosyloxy)flavone